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Ionis Pharmaceuticals IONS

US equityMarket cap rank #1735
$43.50 −$0.04 (-0.09%)
Market closed · Oct 5, 9:20 pm ET · Last extended-hours $43.57 +0.16%
Open$43.75
Prev close$43.54
Day range$42.63 – $43.96
Volume2.87M
Market cap$7.23B
P/E (TTM)–
Dividend yield–

Price chart

Daily bars for up to one year, weekly bars for the 5-year view. Averages are 50/200 trading days (10/40 weeks on the 5-year view). Triangles mark past earnings reports, colored by that day’s move; ticks mark ex-dividend dates — hover either for the date. Volume is the shaded bars under the price; switch on RSI or MACD above for a full-history oscillator panel, not just today’s reading.

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IONS at a glance

IONS last changed hands at $43.50 (down 0.09%). At $7.23B, Ionis Pharmaceuticals is ranked #1735 by size among the 2132 stocks on BeStock.

It is close to the bottom of its 52-week range ($42.63 to $86.74), 49.9% under the high. Holders are behind 37.0% over twelve months, and down 49.6% across the last three months.

On the chart it has slipped under both the 50-day ($53.65) and 200-day ($70.21) moving averages; RSI is 30, and the last 30 sessions moved at roughly 47% annualized volatility.

This summary is put together from the numbers on the page and updates when they do. It describes the data; it is not a forecast or a recommendation.

IONS is not currently one of the 10 holdings in BeStock Momentum, our rules-based momentum strategy.

Since 2021-01-04, the strategy has returned 389% (231.1% for the equal-weight average of BeStock’s coverage over the same stretch). Holdings can change any trading day, not just on a fixed schedule. Backtested performance, updated weekly — not a guarantee of future results, and not a BeStock recommendation.

Performance

Price return over each window, from adjusted daily and weekly closes

1 day
-0.1%
1 week
-4.5%
1 month
-25.2%
3 months
-49.6%
6 months
-41.5%
Year to date
-45.0%
1 year
-37.0%
Day range
$42.63$43.96
52-week range
$42.63$86.74

Technical signals

Full technicals →
Trend readStrong downtrend

1 bullish · 6 bearish of 7 signals

IndicatorValueSignal
Price vs 20-day average-8.2%Bearish
Price vs 50-day average-18.9%Bearish
Price vs 200-day average-38.0%Bearish
50-day vs 200-day50d below 200dBearish
RSI (14)30.3Bearish
MACD (12,26,9)-3.46Bullish
Bollinger band position29%Bearish

Standard indicator readings worked out from daily closes. They describe how the price has behaved, not where it is going.

Key statistics

Bid / Ask$43.37 / $43.89
Average price today$43.44
Volume2.87MAvg (90d) 3.26M
Turnover$124.74M
Turnover rate1.74%of shares outstanding
Volume ratio0.91vs. recent average pace
Day amplitude3.06%
Market cap$7.23B
Float market cap$7.17B
Shares outstanding164.82M
EPS (TTM)-$2.38
P/B16.44
Book value / share$2.65
Earnings yield-1.32%
Net profit (TTM)-$395.52M
Net assets$439.72M
30-day volatility47.1%annualized
Avg daily range (ATR)4.43%of price, 14 days
Max drawdown (1y)-49.7%-49.7% from 1y peak

Quote as of Oct 5, 2026 9:20 pm ET. Prices can lag the live tape. This is background information, not a recommendation.

How IONS ranks on BeStock

Market value#1735 of 2132
Closeness to 52-week high#2024 of 2131
Dollar volume today#821 of 2132

Ranks are among the 2,132 or so U.S.-listed stocks BeStock covers, recalculated whenever prices refresh. A tile is left out when the measure does not apply, such as yield for a stock that pays no dividend.

IONS stock: common questions

How is Ionis Pharmaceuticals stock doing today?

$43.50 is the latest print for IONS, a move of -0.09% against yesterday's close of $43.54. Today's low and high so far: $42.63 and $43.96.

What is IONS worth in total?

Equity value comes to $7.23B at the current price. By that measure it is number 1735 of the 2132 names in our coverage.

Where does IONS sit in its 52-week range?

The year's floor is $42.63 and the ceiling $86.74. Shares are 49.9% away from that ceiling.

Does IONS send cash back through a dividend?

Our data shows no dividend paid by Ionis Pharmaceuticals over the trailing twelve months.

BeStock publishes market data and analysis for information only. Nothing here is investment advice or a solicitation to buy or sell any security, and none of it is tailored to your financial situation, goals, or risk tolerance. Quotes may be delayed and figures can contain errors; check primary sources before you trade. How we source and calculate these pages.

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