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Denali Therapeutics DNLI

US equityMarket cap rank #2435Biotechnology
$19.91 −$0.09 (-0.45%)
Pre-market · Oct 6, 7:20 am ET · After hours $19.91 0.00%
Open$20.09
Prev close$20.00
Day range$19.54 – $20.09
Volume1.72M
Market cap$3.18B
P/E (TTM)–
Dividend yield–

Price chart

Daily bars for up to one year, weekly bars for the 5-year view. Averages are 50/200 trading days (10/40 weeks on the 5-year view). Triangles mark past earnings reports, colored by that day’s move; ticks mark ex-dividend dates — hover either for the date. Volume is the shaded bars under the price; switch on RSI or MACD above for a full-history oscillator panel, not just today’s reading.

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DNLI at a glance

Denali Therapeutics (DNLI) is trading at $19.91, down 0.45% on the day. Its market value of $3.18B makes it the 2435th largest of the 3132 companies we follow.

Over the past 52 weeks it has traded between $13.75 and $27.30, so it sits 27.1% below the top of that range. Holders are ahead 30.8% over twelve months, but down 24.3% across the last three months.

On the chart it has slipped under both the 50-day ($22.80) and 200-day ($21.07) moving averages; RSI is 36, and the last 30 sessions moved at roughly 36% annualized volatility.

13 analysts follow the stock and the average call is "buy". The mean target, $35.09, sits 76.2% over where the stock trades.

This summary is put together from the numbers on the page and updates when they do. It describes the data; it is not a forecast or a recommendation.

BeStock Grade

D
BeStock Grade

Composite of 3 factors below, ranked against the 3131 U.S. stocks BeStock covers.

D
Valuation

Cheaper than usual on its own 5-year P/E history scores higher.

D
Momentum

Trading closer to its 52-week high than most peers scores higher.

B
Wall Street

13 analysts, consensus Buy.

How this is scored: each factor above is a 0–100 percentile rank against every other stock BeStock covers (or, for Wall Street, against the five-point Strong Buy–Sell scale). The overall grade is the plain average of whichever factors apply to this stock — no factor is weighted more than another. That average maps to a letter: A ≥ 85, B ≥ 70, C ≥ 50, D ≥ 30, otherwise F. Recomputed from the data on this page as prices and filings update — it describes where a stock ranks today, not a forecast, and not a BeStock recommendation to buy or sell.

DNLI is not currently one of the 10 holdings in BeStock Momentum, our rules-based momentum strategy.

Since 2021-01-04, the strategy has returned 389% (231.1% for the equal-weight average of BeStock’s coverage over the same stretch). Holdings can change any trading day, not just on a fixed schedule. Backtested performance, updated weekly — not a guarantee of future results, and not a BeStock recommendation.

Price forecast

What Wall Street analysts and Morningstar's fair-value model expect for the stock

Analyst price target (avg)$35.09+76.2% vs. current price
Consensus ratingBuy13 analysts covering
Morningstar fair value$20.26Close to fair value

Wall Street’s average 12-month target is $35.09, 76.2% above today’s price, with a consensus rating of Buy. Morningstar’s fair value model puts the stock at $20.26, so shares trade 1.7% below that estimate. On earnings multiple, it sits in the 68th percentile of its own five-year valuation range (pricier than usual).

Figures are Wall Street analyst consensus and Morningstar’s independent fair-value model, sourced as noted above.

Performance

Price return over each window, from adjusted daily and weekly closes

1 day
-0.5%
1 week
-5.1%
1 month
-12.7%
3 months
-24.3%
6 months
+2.7%
Year to date
+20.6%
1 year
+30.8%
Day range
$19.54$20.09
52-week range
$13.75$27.30

Technical signals

Full technicals →
Trend readLeaning bearish

2 bullish · 5 bearish of 7 signals

IndicatorValueSignal
Price vs 20-day average-3.8%Bearish
Price vs 50-day average-12.7%Bearish
Price vs 200-day average-5.5%Bearish
50-day vs 200-day50d above 200dBullish
RSI (14)35.7Bearish
MACD (12,26,9)-0.73Bullish
Bollinger band position19%Bearish

Standard indicator readings worked out from daily closes. They describe how the price has behaved, not where it is going.

Key statistics

Bid / Ask$19.80 / $21.49
Average price today$19.86
Volume1.72MAvg (90d) 1.68M
Turnover$34.11M
Turnover rate1.11%of shares outstanding
Volume ratio0.88vs. recent average pace
Day amplitude2.78%
Market cap$3.18B
Float market cap$3.09B
Shares outstanding155.09M
EPS (TTM)-$2.97
P/B3.81
Book value / share$5.23
Earnings yield-0.54%
Net profit (TTM)-$474.75M
Net assets$835.20M
30-day volatility35.6%annualized
Avg daily range (ATR)4.20%of price, 14 days
Max drawdown (1y)-27.5%-26.8% from 1y peak

Quote as of Oct 6, 2026 7:20 am ET. Prices can lag the live tape. This is background information, not a recommendation.

How DNLI ranks on BeStock

Market value#2434 of 3131
Closeness to 52-week high#2089 of 3126
Dollar volume today#1658 of 3131

Ranks are among the 3,131 or so U.S.-listed stocks BeStock covers, recalculated whenever prices refresh. A tile is left out when the measure does not apply, such as yield for a stock that pays no dividend.

DNLI stock: common questions

What is DNLI's latest share price?

$19.91 is the latest print for DNLI, a move of -0.45% against yesterday's close of $20.00. Today's low and high so far: $19.54 and $20.09.

How big is Denali Therapeutics?

Equity value comes to $3.18B at the current price. By that measure it is number 2435 of the 3132 names in our coverage.

Where does DNLI sit in its 52-week range?

The year's floor is $13.75 and the ceiling $27.30. Shares are 27.1% away from that ceiling.

Does DNLI send cash back through a dividend?

Our data shows no dividend paid by Denali Therapeutics over the trailing twelve months.

Do Wall Street analysts like DNLI?

Of 13 analysts, 100% say buy, 0% hold and 0% sell. Price targets average $35.09, with the most cautious at $26.00 and the most optimistic at $42.00.

BeStock publishes market data and analysis for information only. Nothing here is investment advice or a solicitation to buy or sell any security, and none of it is tailored to your financial situation, goals, or risk tolerance. Quotes may be delayed and figures can contain errors; check primary sources before you trade. How we source and calculate these pages.

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