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Denali Therapeutics DNLI

US equityMarket cap rank #2435Biotechnology
$19.91 −$0.09 (-0.45%)
Pre-market · Oct 6, 8:20 am ET · After hours $19.91 0.00%
Open$20.09
Prev close$20.00
Day range$19.54 – $20.09
Volume1.72M
Market cap$3.18B
P/E (TTM)–
Dividend yield–

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership99.0%-4.34 pts vs. prior quarter
Institutions holding351-2 vs. prior quarter
Insider trades (recent)31 buys / 17 sellsNet buying
Short interest10.72% of floatDays to cover 12.0 · as of 15 Sep 2026
Short-sale volume share21.4%5-day average of daily volume

Short-sale volume as % of daily volume

16%20%25%29%Sep '26Sep '26Oct '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: +$751.7K (6 inflow days, 14 outflow days).

The five largest holders on file together own 37.3% of shares outstanding.

Largest holders

  • T. Rowe Price Group, Inc.12.08%
  • BlackRock8.77%
  • Baillie Gifford7.48%
  • Vanguard Capital Management, LLC4.55%
  • State Street Global Advisors4.41%
  • Temasek Holdings4.39%
  • Vanguard Portfolio Management, LLC4.05%
  • UBS Asset Management3.93%

By investor type

  • Mutual Fund75.71%
  • Hedge Fund10.10%
  • VC/PE Fund7.83%
  • Individual/Insider2.97%
  • Public Company2.37%
  • Sovereign Wealth Fund1.78%
  • Private Company0.57%
  • Government Pension Fund0.52%

Reported short interest has risen from 10.05% to 10.72% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).

Short interest, by report

Report dateShares short% of floatDays to cover
15 Sep 2026 17,139,415 10.7% 12.0
31 Aug 2026 16,642,362 10.4% 17.5
14 Aug 2026 17,959,465 11.2% 12.4
31 Jul 2026 17,434,654 11.0% 12.1
15 Jul 2026 16,035,916 10.1% 8.4
30 Jun 2026 15,949,089 10.0% 7.0

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