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Denali 制药 DNLI

美股市值排名 #2427生物科技

$20.07 +$0.35 (+1.77%)

休市 · Nov 6, 8:10 pm ET · 最新盘后价 $20.16 +0.45%

开盘$19.97

昨收$19.72

当日区间$19.78 – $20.36

成交量1.59M

市值$3.22B

市盈率（TTM）–

股息率–

股权结构与仓位

谁在持有、谁在做空，以及大资金的流向

机构持股比例99.9%-4.23 个百分点，较上季度

持仓机构数356+2 ，较上季度

内部人近期交易31次买入 / 17次卖出净买入

空头持仓比例9.68% 占流通股回补天数 8.1 · 截至 15 Oct 2026

卖空成交量占比20.7%近5日成交量平均占比

卖空成交量占当日成交量比例

大单净流入，近20个交易日

大单买入减卖出的净额（美元）。该窗口期内：+$7.28M（13个净流入日，7个净流出日）。

按单量净流入，近20个交易日

超大单/大单近似机构级别交易；中单/小单近似散户级别交易。各档买入减卖出净额，按窗口期累计。

已披露的前五大股东合计持有37.3%的流通股。

最大股东

T. Rowe Price Group, Inc.12.08%
BlackRock8.77%
Baillie Gifford7.48%
Vanguard Capital Management, LLC4.55%
State Street Global Advisors4.41%
Temasek Holdings4.39%
Vanguard Portfolio Management, LLC4.05%
UBS Asset Management3.93%

按投资者类型

Mutual Fund76.53%
Hedge Fund10.10%
VC/PE Fund7.82%
Individual/Insider2.97%
Public Company2.37%
Sovereign Wealth Fund1.78%
Private Company0.57%
Government Pension Fund0.52%

过去6次双周报告中（31 Jul 2026至15 Oct 2026），空头持仓占流通股比例已从10.99%降至9.68%。

近期机构持仓变动

股东	类型	期间	持股变动	新持股比例
T. Rowe Price Group, Inc.	Mutual Fund	2026/Q3	+8,331,774	12.1%
Macquarie Investment Management Business Trust	Mutual Fund	2026/Q3	+2,093,739	1.4%
BNPP Asset Management Holding	Mutual Fund	2026/Q3	+1,071,130	0.7%
BlackRock	Mutual Fund	2026/Q3	+991,979	8.8%
State Street Global Advisors	Mutual Fund	2026/Q3	+777,303	4.4%
Holocene Advisors, LP	Hedge Fund	2026/Q3	+709,796	2.4%
Goldman Sachs Asset Management, L.P.	Mutual Fund	2026/Q3	+527,880	2.0%
Citigroup Inc.	Public Company	2026/Q3	+448,000	0.3%
Dafna Capital Management, LLC	Hedge Fund	2026/Q3	+420,514	0.5%
Vanguard Portfolio Management, LLC	Mutual Fund	2026/Q3	+356,897	4.1%
ExodusPoint Capital Management, LP	Hedge Fund	2026/Q3	+336,567	0.2%
AQR Capital Management	Hedge Fund	2026/Q3	+283,999	0.2%
Geode Capital Management, LLC	Mutual Fund	2026/Q3	+246,228	2.5%
Teachers Insurance and Annuity Association-College Retirement Equities Fund	Mutual Fund	2026/Q3	+238,687	0.3%
Pictet Asset Management Limited	Mutual Fund	2026/Q3	+232,341	1.7%

按报告期列出的机构买卖动态，变动幅度从大到小排列。

内部人交易

日期	内部人	职位	交易类型	股数	价格	交易后持股
3 Sep 2026	Peter Chin	Acting Chief Medical Officer & Head of Development	Open Market Disposition	-1,654	$22.29	204,538
1 Sep 2026	Nancy Thornberry	Independent Director	Automatic Disposition	-11,439	$23.74	13,278
31 Aug 2026	Alexander Schuth	Co-Founder, CFO, COO & Secretary	Automatic Disposition	-2,768	$23.44	667,269
11 Aug 2026	Ryan Watts	Chief Executive Officer	Other Disposition	-32,220	–	2,232,302
10 Aug 2026	Alexander Schuth	Co-Founder, CFO, COO & Secretary	Open Market Disposition	-2,857	$25.07	670,037
2 Jun 2026	Jay Flatley	Independent Director	Other Acquisition	+6,408	–	6,408
2 Jun 2026	Jay Flatley	Independent Director	Other Derivative Acquisition	+19,226	$19.66	19,226
2 Jun 2026	Julian Baker	Independent Chairperson	Other Acquisition	+12,816	–	28,664
2 Jun 2026	Julian Baker	Independent Chairperson	Other Derivative Acquisition	+19,226	$19.66	19,226
2 Jun 2026	David Schenkein	Independent Director	Other Acquisition	+6,408	–	6,408
2 Jun 2026	David Schenkein	Independent Director	Other Derivative Acquisition	+19,226	$19.66	19,226
2 Jun 2026	Peter Klein	Independent Director	Other Acquisition	+6,408	–	6,408
2 Jun 2026	Peter Klein	Independent Director	Other Derivative Acquisition	+19,226	$19.66	19,226
2 Jun 2026	Jennifer Cook	Independent Director	Other Acquisition	+6,408	–	6,408
2 Jun 2026	Jennifer Cook	Independent Director	Other Derivative Acquisition	+19,226	$19.66	19,226
2 Jun 2026	Timothy Van Hauwermeiren		Other Acquisition	+6,408	–	17,040
2 Jun 2026	Timothy Van Hauwermeiren		Other Derivative Acquisition	+19,226	$19.66	19,226
2 Jun 2026	Steve Krognes	Independent Director	Other Acquisition	+6,408	–	6,408
2 Jun 2026	Steve Krognes	Independent Director	Other Derivative Acquisition	+19,226	$19.66	19,226
2 Jun 2026	Nancy Thornberry	Independent Director	Other Acquisition	+6,408	–	6,408

数据来自Form 4/Form 144申报文件。负数为减持（出售、赠予或代扣税款股份），正数为增持。

空头持仓（按报告期）

报告日期	空头股数	占流通股比例	回补天数
15 Oct 2026	15,475,322	9.7%	8.1
30 Sep 2026	15,463,975	9.7%	7.6
15 Sep 2026	17,139,415	10.7%	12.0
31 Aug 2026	16,642,362	10.4%	17.5
14 Aug 2026	17,959,465	11.2%	12.4
31 Jul 2026	17,434,654	11.0%	12.1

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