结构治疗 GPCR
$20.35 +$1.27 (+6.66%)
休市 · Nov 6, 8:10 pm ET · 最新盘后价 $20.00 -1.72%
开盘$19.44
昨收$19.08
当日区间$18.70 – $21.31
成交量1.62M
市值$1.45B
市盈率（TTM）–
股息率–
股权结构与仓位
谁在持有、谁在做空，以及大资金的流向
机构持股比例102.5%-1.81 个百分点，较上季度
持仓机构数245-6 ，较上季度
内部人近期交易28次买入 / 22次卖出净买入
空头持仓比例10.02% 占流通股回补天数 4.8 · 截至 15 Oct 2026
卖空成交量占比15.5%近5日成交量平均占比
卖空成交量占当日成交量比例
大单净流入，近20个交易日
大单买入减卖出的净额（美元）。该窗口期内：−$15.50M（7个净流入日，13个净流出日）。
按单量净流入，近20个交易日
超大单/大单近似机构级别交易；中单/小单近似散户级别交易。各档买入减卖出净额，按窗口期累计。
已披露的前五大股东合计持有48.3%的流通股。
最大股东
按投资者类型
过去6次双周报告中（31 Jul 2026至15 Oct 2026），空头持仓占流通股比例已从8.51%升至10.02%。
近期机构持仓变动
| 股东 | 类型 | 期间 | 持股变动 | 新持股比例 |
|---|---|---|---|---|
| RTW Investments, LP | Hedge Fund | 2026/Q3 | +1,607,507 | 2.3% |
| OrbiMed Advisors LLC | VC/PE Fund | 2026/Q3 | +733,997 | 3.1% |
| Morgan Stanley | Public Company | 2026/Q3 | +498,980 | 3.8% |
| Deep Track Capital, LP | VC/PE Fund | 2026/Q3 | +460,224 | 10.6% |
| Norges Bank Investment Management | Sovereign Wealth Fund | 2026/Q3 | +426,977 | 0.6% |
| Bank of America Corporation | Public Company | 2026/Q3 | +336,747 | 0.7% |
| Davern Capital Partners, LP | Hedge Fund | 2026/Q3 | +319,598 | 0.6% |
| Deerfield Management Company, L.P. | Hedge Fund | 2026/Q3 | +318,007 | 1.5% |
| HongShan Capital Advisors Limited | VC/PE Fund | 2026/Q3 | +254,750 | 0.4% |
| Parkman Healthcare Partners LLC | Hedge Fund | 2026/Q3 | +253,568 | 0.7% |
| abrdn plc | Mutual Fund | 2026/Q3 | +248,106 | 0.9% |
| American Century Investment Management | Mutual Fund | 2026/Q3 | +244,148 | 2.4% |
| Marshall Wace LLP | Hedge Fund | 2026/Q3 | +198,485 | 0.4% |
| Nextbio Capital Management LP | Hedge Fund | 2026/Q3 | +179,257 | 0.4% |
| UBS Asset Management | Mutual Fund | 2026/Q3 | +166,067 | 0.5% |
按报告期列出的机构买卖动态，变动幅度从大到小排列。
内部人交易
| 日期 | 内部人 | 职位 | 交易类型 | 股数 | 价格 | 交易后持股 |
|---|---|---|---|---|---|---|
| 20 Sep 2026 | Blai Coll | Chief Medical Officer | Other Disposition | -4,008 | – | 15,098 |
| 20 Sep 2026 | Blai Coll | Chief Medical Officer | Other Derivative Acquisition | +4,008 | – | 5,165 |
| 20 Sep 2026 | Blai Coll | Chief Medical Officer | Open Market Derivative Dispositi | -4,008 | – | 1,157 |
| 17 Sep 2026 | Blai Coll | Chief Medical Officer | Sale to Issuer | -3,542 | $35.01 | 15,098 |
| 31 Aug 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Derivative Exercise and Sale | -17,817 | – | 53,578 |
| 31 Aug 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Derivative Exercise and Sale | -5,939 | $47.83 | – |
| 17 Aug 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Derivative Exercise and Sale | -11,817 | – | 53,578 |
| 17 Aug 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Derivative Exercise and Sale | -3,939 | $55.05 | – |
| 5 Aug 2026 | John Berrios | Other Acquisition | +140,766 | – | 140,766 | |
| 5 Aug 2026 | John Berrios | Other Derivative Acquisition | +174,612 | $17.54 | 174,612 | |
| 3 Aug 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Derivative Exercise and Sale | -11,817 | – | 53,578 |
| 3 Aug 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Derivative Exercise and Sale | -3,939 | $50.03 | – |
| 13 Jul 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Other Acquisition | +7,878 | – | – |
| 13 Jul 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Open Market Disposition | -7,878 | $51.71 | – |
| 13 Jul 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Derivative Exercise and Sale | -23,634 | – | 53,578 |
| 13 Jul 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Other Derivative Acquisition | +7,878 | – | 7,878 |
| 13 Jul 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Open Market Derivative Dispositi | -7,878 | – | – |
| 24 Jun 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Other Acquisition | +7,878 | – | – |
| 24 Jun 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Open Market Disposition | -7,878 | $49.08 | – |
| 24 Jun 2026 | Xichen Lin | Chief Scientific Officer & GM of Structure Shanghai | Derivative Exercise and Sale | -23,634 | – | 53,578 |
数据来自Form 4/Form 144申报文件。负数为减持（出售、赠予或代扣税款股份），正数为增持。
空头持仓（按报告期）
| 报告日期 | 空头股数 | 占流通股比例 | 回补天数 |
|---|---|---|---|
| 15 Oct 2026 | 7,147,328 | 10.0% | 4.8 |
| 30 Sep 2026 | 7,540,480 | 10.6% | 5.2 |
| 15 Sep 2026 | 6,605,011 | 9.3% | 5.2 |
| 31 Aug 2026 | 5,854,907 | 8.2% | 7.9 |
| 14 Aug 2026 | 6,079,970 | 8.5% | 10.4 |
| 31 Jul 2026 | 6,049,938 | 8.5% | 11.5 |
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