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Prime Medicine PRME

US equityMarket cap rank #3547
$3.65 −$0.25 (-6.41%)
Market open · Oct 8, 12:30 pm ET · After hours $3.88 -0.42%
Open$3.83
Prev close$3.90
Day range$3.58 – $3.90
Volume3.46M
Market cap$662.03M
P/E (TTM)–
Dividend yield–

Fundamentals

Latest reported quarter: Q2, ended Jun 2026

Revenue$1.15M+3.5% YoY
Operating profit-$43.29M+18.9% YoY
Net profit-$42.11M+19.9% YoY
Diluted EPS-$0.24+41.5% YoY
Free cash flow-$41.09M+4.4% YoY
Operating cash flow-$41.05M

Revenue, last 8 quarters

$209.0KSep '24$2.2MDec '24$1.5MMar '25$1.1MJun '25$1.2MSep '25$838.0KDec '25$856.0KMar '26$1.2MJun '26

Net profit, last 8 quarters

$-52.5MSep '24$-42.3MDec '24$-51.9MMar '25$-52.6MJun '25$-50.6MSep '25$-46.1MDec '25$-49.1MMar '26$-42.1MJun '26

Diluted EPS by quarter

-0.44Sep '24-0.31Dec '24-0.40Mar '25-0.41Jun '25-0.32Sep '25-0.24Dec '25-0.28Mar '26-0.24Jun '26

Free cash flow by quarter

$-27.2MSep '24$14.5MDec '24$-51.3MMar '25$-43.0MJun '25$-35.3MSep '25$-37.5MDec '25$-42.9MMar '26$-41.1MJun '26

Annual revenue

$5.2MFY20$0.0FY21$0.0FY22$0.0FY23$3.0MFY24$4.6MFY25

Profitability & balance sheet

Operating margin-4,824.9%
Net margin-4,613.1%
Return on equity-18.2%
Return on assets-71.2%
Return on invested capital-16.9%
Current ratio3.05
Liabilities / assets84.0%
Cash & investments$47.45M
Total debt$103.51M
Net cash (debt)-$56.06M

Income statement

Line item 2026 Q2 2026 Q1 2025 ANNUAL 2025 Q4 2025 Q3
Total Revenue as Reported $1.15M $856,000.00 $4.63M $838,000.00 $1.23M
Total Operating Revenue $1.15M $856,000.00 $4.63M $838,000.00 $1.23M
Operating Expense $44.44M $51.51M $212.98M $49.45M $55.20M
Selling and Admin Expenses $11.04M $17.41M $52.35M $14.74M $11.21M
-General & Admin Expense $11.04M $17.41M $52.35M $14.74M $11.21M
Research & Development $33.40M $34.11M $160.64M $34.71M $43.99M
Operating Profit -$43.29M -$50.65M -$208.35M -$48.61M -$53.97M
Net Non-Operating Interest Income (Expense) $788,000.00 $1.02M $4.15M $1.08M $1.14M
Non-Operating Interest Income $788,000.00 $1.02M $4.15M $1.08M $1.14M
Other Income (Expense) $388,000.00 $511,000.00 $3.06M $1.45M $2.25M
Securities Amortization -$333,000.00 -$460,000.00 -$2.48M -$858,000.00 -$752,000.00
Other Non-Operating Income (Expenses) $55,000.00 $51,000.00 $148,000.00 $49,000.00 $44,000.00
Pretax Profit -$42.11M -$49.12M -$201.14M -$46.08M -$50.58M
Net Profit -$42.11M -$49.12M -$201.14M -$46.08M -$50.58M
Profit from Continuing Operations -$42.11M -$49.12M -$201.14M -$46.08M -$50.58M
Net Income to Parent Company -$42.11M -$49.12M -$201.14M -$46.08M -$50.58M
Net Income to Common Stockholders -$42.11M -$49.12M -$201.14M -$46.08M -$50.58M
Basic EPS -$0.24 -$0.28 -$1.35 -$0.24 -$0.32
Diluted EPS -$0.24 -$0.28 -$1.35 -$0.24 -$0.32
Gain on Sale of Security – – $432,000.00 $539,000.00 $1.45M

Balance sheet

Line item 2026 Q2 2026 Q1 2025 ANNUAL 2025 Q4 2025 Q3
Total Assets $249.04M $294.73M $342.73M $342.73M $385.01M
Total Current Assets $96.80M $137.89M $181.29M $181.29M $231.41M
Cash and Cash Equivalents & Short-Term Investments $47.45M $135.50M $177.68M $177.68M $213.29M
-Cash and Cash Equivalents $47.45M $64.11M $63.03M $63.03M $71.40M
Prepaid Assets $1.36M $1.97M $2.94M $2.94M $2.49M
Other Current Assets $95.45M $421,000.00 $674,000.00 $674,000.00 $15.63M
Total Non-Current Assets $152.24M $156.84M $161.44M $161.44M $153.61M
Other Non-Current Assets $152.24M $14.69M $14.69M $14.69M $13.69M
Total Liabilities $209.23M $218.03M $221.87M $221.87M $223.19M
Total Current Liabilities $31.69M $36.29M $37.45M $37.45M $35.02M
-Accounts Payable $5.81M $12.33M $8.89M $8.89M $9.35M
Current Accrued Expenses $4.65M $3.76M $3.56M $3.56M $2.18M
-Current Capital Lease Obligation $8.97M $8.55M $8.14M $8.14M $7.71M
Other Current Liabilities $31.69M $2.15M $1.70M $1.70M $2.06M
Total Non-Current Liabilities $177.54M $181.74M $184.42M $184.42M $188.17M
Long Term Debt and Capital Lease Obligation $103.51M $105.97M $108.29M $108.29M $110.42M
-Long Term Capital Lease Obligation $103.51M $105.97M $108.29M $108.29M $110.42M
Total Equity $39.81M $76.70M $120.87M $120.87M $161.82M
Stockholders' Equity $2.00B $76.70M $120.87M $120.87M $161.82M
Additional Paid-In Capital $1.02B $1.01B $1.01B $1.01B $1.00B
Retained Earnings $979.59M -$937.48M -$888.35M -$888.35M -$842.28M
-Short Term Investments – $71.39M $114.65M $114.65M $141.89M
Net PPE – $142.15M $146.75M $146.75M $139.92M
-Gross PPE – $164.44M $167.18M $167.18M $158.47M
-Accumulated Depreciation – -$22.29M -$20.43M -$20.43M -$18.56M
Payables – $12.33M $8.89M $8.89M $9.35M
Short-Term Debt and Capital Lease Obligation – $8.55M $8.14M $8.14M $7.71M
Current Deferred Liabilities – $7.32M $7.82M $7.82M $6.95M
Non-Current Deferred Liabilities – $75.78M $76.13M $76.13M $77.75M
Capital Stock – $2,000.00 $2,000.00 $2,000.00 $2,000.00
-Common Stock – $2,000.00 $2,000.00 $2,000.00 $2,000.00
Gains/Losses Not Affecting Retained Earnings – -$1,000.00 $82,000.00 $82,000.00 $33,000.00

Cash flow

Line item 2026 Q2 2026 Q1 2025 ANNUAL 2025 Q4 2025 Q3
Operating Cash Flow -$41.05M -$42.71M -$162.56M -$37.26M -$35.04M
Net cash flow from continuing operations -$41.05M -$42.71M -$162.56M -$37.26M -$35.04M
Net Income from Continuing Operations -$42.11M -$49.12M -$201.14M -$46.08M -$50.58M
Depreciation & Depletion & Amortization $1.79M $1.86M $7.32M $1.88M $1.88M
Other Non-Cash Items $2.87M $2.84M $9.70M $2.60M $2.33M
Change in Working Capital -$8.14M -$2.50M -$5.34M $1.16M $609,000.00
-Change in Receivables $0.00 $0.00 – – $120,000.00
-Change in Prepaid Assets $659,000.00 $1.22M $4.55M $2.60M $1.30M
-Change in Payables and Accrued Expense -$5.64M -$950,000.00 -$164,000.00 $1.02M $1.97M
-Change in Other Current Liabilities -$69,000.00 -$1.92M -$5.36M -$1.71M -$1.60M
-Change In Other Working Capital -$3.09M -$856,000.00 -$4.36M -$751,000.00 -$1.18M
Net cash flow from investing $24.03M $43.39M -$108.76M $28.33M -$92.12M
Net Cash Flow from Continuing Investing Activities $24.03M $43.39M -$108.76M $28.33M -$92.12M
Net PPE Purchase and Sale -$46,000.00 -$214,000.00 -$4.53M -$290,000.00 -$247,000.00
Net Investment Purchase and Sale $24.08M $43.61M -$104.23M $28.62M -$91.88M
Financing Cash Flow $361,000.00 $393,000.00 $151.51M $562,000.00 $144.75M
Net Cash Flow from Continuing Financing Activities $361,000.00 $393,000.00 $151.51M $562,000.00 $144.75M
Proceeds from Stock Option Exercised $361,000.00 $393,000.00 $1.12M $552,000.00 $373,000.00
Ending Cash Balance $61.14M $77.80M $76.72M $76.72M $85.09M
Net Change in Cash -$16.66M $1.07M -$119.82M -$8.36M $17.59M
Beginning Cash Balance $77.80M $76.72M $196.54M $85.09M $67.50M
Free Cash Flow -$41.09M -$42.92M -$167.10M -$37.55M -$35.29M
Net Common Stock Issuance – – $138.39M $10,000.00 –
Net Other Financing Charges – – $12.00M $0.00 $6.00M

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