股票 › SYRE
斯派尔治疗 SYRE
美股市值排名 #1451
$103.86 +$7.27 (+7.53%)
休市 · Nov 7, 5:50 am ET · 最新盘后价 $103.00 -0.83%
开盘$98.35
昨收$96.59
当日区间$97.29 – $104.30
成交量1.64M
市值$9.86B
市盈率（TTM）–
股息率–
股权结构与仓位
谁在持有、谁在做空，以及大资金的流向
机构持股比例112.3%+1.92 个百分点，较上季度
持仓机构数347+16 ，较上季度
内部人近期交易13次买入 / 37次卖出净卖出
空头持仓比例13.57% 占流通股回补天数 7.3 · 截至 15 Oct 2026
卖空成交量占比27.3%近5日成交量平均占比
卖空成交量占当日成交量比例
大单净流入，近20个交易日
大单买入减卖出的净额（美元）。该窗口期内：−$2.53M（8个净流入日，12个净流出日）。
按单量净流入，近20个交易日
超大单/大单近似机构级别交易；中单/小单近似散户级别交易。各档买入减卖出净额，按窗口期累计。
已披露的前五大股东合计持有36.9%的流通股。
最大股东
按投资者类型
过去6次双周报告中（31 Jul 2026至15 Oct 2026），空头持仓占流通股比例已从13.98%降至13.57%。
近期机构持仓变动
| 股东 | 类型 | 期间 | 持股变动 | 新持股比例 |
|---|---|---|---|---|
| Assenagon Asset Management S.A. | Mutual Fund | 2026/Q3 | +599,224 | 0.7% |
| Paradigm Biocapital Advisors LP | Hedge Fund | 2026/Q3 | +616,672 | 5.1% |
| Vanguard Portfolio Management, LLC | Mutual Fund | 2026/Q3 | +1,744,968 | 2.6% |
| Adage Capital Management, L.P. | Hedge Fund | 2026/Q3 | +1,722,300 | 2.0% |
| T. Rowe Price Group, Inc. | Mutual Fund | 2026/Q3 | +1,362,125 | 3.4% |
| FMR | Mutual Fund | 2026/Q3 | +1,245,163 | 14.8% |
| Holocene Advisors, LP | Hedge Fund | 2026/Q3 | +1,015,170 | 1.2% |
| BlackRock | Mutual Fund | 2026/Q3 | +985,384 | 7.4% |
| Capital Research | Mutual Fund | 2026/Q3 | +858,056 | 3.7% |
| Marshall Wace LLP | Hedge Fund | 2026/Q3 | +852,434 | 1.1% |
| Geode Capital Management, LLC | Mutual Fund | 2026/Q3 | +841,353 | 2.9% |
| The Goldman Sachs Group, Inc. | Public Company | 2026/Q3 | +678,096 | 0.9% |
| Janus Henderson Group plc | Mutual Fund | 2026/Q3 | +550,772 | 2.5% |
| Bank of America Corporation | Public Company | 2026/Q3 | +537,647 | 2.0% |
| Perceptive Advisors LLC | VC/PE Fund | 2026/Q3 | +536,271 | 4.9% |
按报告期列出的机构买卖动态，变动幅度从大到小排列。
内部人交易
| 日期 | 内部人 | 职位 | 交易类型 | 股数 | 价格 | 交易后持股 |
|---|---|---|---|---|---|---|
| 30 Sep 2026 | Cameron Turtle | Chief Executive Officer | Automatic Disposition | -15,000 | $93.91 | 537,540 |
| 30 Sep 2026 | Heidy King-Jones | Chief Legal Officer | Derivative Exercise and Sale | -28,933 | $93.46 | 2,845 |
| 30 Sep 2026 | Scott Burrows | Chief Financial Officer | Derivative Exercise and Sale | -25,000 | $93.57 | 46,024 |
| 29 Sep 2026 | Scott Burrows | Chief Financial Officer | Intent to Sell (Form 144) | -17,500 | $89.89 | – |
| 1 Sep 2026 | Scott Burrows | Chief Financial Officer | Open Market Disposition | -18,232 | $89.35 | 46,024 |
| 1 Sep 2026 | Heidy King-Jones | Chief Legal Officer | Derivative Exercise and Sale | -28,399 | $90.00 | 2,845 |
| 31 Aug 2026 | Cameron Turtle | Chief Executive Officer | Automatic Disposition | -15,000 | $89.07 | 552,540 |
| 31 Aug 2026 | Heidy King-Jones | Chief Legal Officer | Intent to Sell (Form 144) | -46,665 | $89.33 | – |
| 31 Aug 2026 | Scott Burrows | Chief Financial Officer | Derivative Exercise and Sale | -7,500 | $89.04 | 46,024 |
| 6 Aug 2026 | Jeffrey Albers | Independent Chairperson | Automatic Disposition | -18,000 | $104.68 | 9,360 |
| 6 Aug 2026 | Jeffrey Albers | Independent Chairperson | Derivative Exercise and Sale | -5,000 | $104.47 | 9,360 |
| 2 Aug 2026 | Cameron Turtle | Chief Executive Officer | Automatic Disposition | -15,000 | $97.46 | 567,540 |
| 2 Aug 2026 | Scott Burrows | Chief Financial Officer | Derivative Exercise and Sale | -7,500 | $97.10 | 30,518 |
| 30 Jun 2026 | Cameron Turtle | Chief Executive Officer | Automatic Disposition | -15,000 | $88.91 | 582,540 |
| 30 Jun 2026 | Scott Burrows | Chief Financial Officer | Derivative Exercise and Sale | -7,500 | $88.37 | 30,518 |
| 30 Jun 2026 | Sheldon Sloan | Chief Medical Officer | Derivative Exercise and Sale | -8,334 | $88.34 | – |
| 24 Jun 2026 | Scott Burrows | Chief Financial Officer | Derivative Exercise and Sale | -15,000 | $87.14 | 30,518 |
| 22 Jun 2026 | Fairmount Funds Management LLC | Private Disposition | -4,018,101 | $85.31 | – | |
| 22 Jun 2026 | Fairmount Funds Management LLC | Derivative Exercise and Sale | -666,680 | $85.31 | – | |
| 21 Jun 2026 | Michael Henderson | Independent Director | Automatic Disposition | -20,000 | $100.00 | 68,606 |
数据来自Form 4/Form 144申报文件。负数为减持（出售、赠予或代扣税款股份），正数为增持。
空头持仓（按报告期）
| 报告日期 | 空头股数 | 占流通股比例 | 回补天数 |
|---|---|---|---|
| 15 Oct 2026 | 12,505,491 | 13.6% | 7.3 |
| 30 Sep 2026 | 12,844,608 | 14.6% | 8.9 |
| 15 Sep 2026 | 12,129,443 | 13.8% | 11.6 |
| 31 Aug 2026 | 11,859,975 | 13.5% | 9.7 |
| 14 Aug 2026 | 11,755,434 | 13.3% | 16.0 |
| 31 Jul 2026 | 12,143,879 | 14.0% | 13.5 |
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