节律制药 RYTM
$112.28 +$7.26 (+6.91%)
休市 · Nov 6, 8:10 pm ET · 最新盘后价 $112.80 +0.46%
开盘$107.10
昨收$105.02
当日区间$104.31 – $113.29
成交量4.94M
市值$7.78B
市盈率（TTM）–
股息率–
股权结构与仓位
谁在持有、谁在做空，以及大资金的流向
机构持股比例114.1%-0.04 个百分点，较上季度
持仓机构数387-1 ，较上季度
内部人近期交易28次买入 / 22次卖出净买入
空头持仓比例15.98% 占流通股回补天数 13.5 · 截至 15 Oct 2026
卖空成交量占比13.9%近5日成交量平均占比
卖空成交量占当日成交量比例
大单净流入，近20个交易日
大单买入减卖出的净额（美元）。该窗口期内：−$16.12M（7个净流入日，13个净流出日）。
按单量净流入，近20个交易日
超大单/大单近似机构级别交易；中单/小单近似散户级别交易。各档买入减卖出净额，按窗口期累计。
已披露的前五大股东合计持有36.4%的流通股。
最大股东
按投资者类型
过去6次双周报告中（31 Jul 2026至15 Oct 2026），空头持仓占流通股比例已从13.76%升至15.98%。
近期机构持仓变动
| 股东 | 类型 | 期间 | 持股变动 | 新持股比例 |
|---|---|---|---|---|
| Assenagon Asset Management S.A. | Mutual Fund | 2026/Q3 | +176,882 | 0.5% |
| J.P. Morgan Asset Management, Inc. | Mutual Fund | 2026/Q3 | +1,055,421 | 3.7% |
| T. Rowe Price Group, Inc. | Mutual Fund | 2026/Q3 | +911,295 | 3.7% |
| Norges Bank Investment Management | Sovereign Wealth Fund | 2026/Q3 | +619,631 | 1.0% |
| Capital Research | Mutual Fund | 2026/Q3 | +522,600 | 2.5% |
| Federated Hermes, Inc. | Mutual Fund | 2026/Q3 | +499,413 | 2.6% |
| Artal Group S.A. | VC/PE Fund | 2026/Q3 | +410,764 | 1.7% |
| Morgan Stanley | Public Company | 2026/Q3 | +378,264 | 1.4% |
| State Street Global Advisors | Mutual Fund | 2026/Q3 | +301,678 | 3.7% |
| Pictet Asset Management Limited | Mutual Fund | 2026/Q3 | +290,739 | 1.4% |
| Westfield Capital Management Company, L.P. | Mutual Fund | 2026/Q3 | +279,472 | 3.2% |
| Goldman Sachs Asset Management, L.P. | Mutual Fund | 2026/Q3 | +246,036 | 0.7% |
| Wellington Management Group | Mutual Fund | 2026/Q3 | +214,990 | 0.7% |
| Perceptive Advisors LLC | VC/PE Fund | 2026/Q3 | +212,500 | 3.8% |
| Duquesne Family Office LLC | Family Office/Trust | 2026/Q3 | +203,618 | 0.3% |
按报告期列出的机构买卖动态，变动幅度从大到小排列。
内部人交易
| 日期 | 内部人 | 职位 | 交易类型 | 股数 | 价格 | 交易后持股 |
|---|---|---|---|---|---|---|
| 13 Sep 2026 | David Meeker | Chairperson & CEO | Derivative Exercise and Sale | -50,000 | $105.19 | 239,258 |
| 30 Aug 2026 | Hunter Smith | Chief Financial Officer | Automatic Disposition | -5,587 | $106.20 | 114,024 |
| 30 Aug 2026 | Hunter Smith | Chief Financial Officer | Derivative Exercise and Sale | -57,187 | $106.20 | 114,024 |
| 16 Aug 2026 | Manher Joshi | Chief Medical Officer | Other Derivative Acquisition | +25,000 | – | 25,000 |
| 16 Aug 2026 | Manher Joshi | Chief Medical Officer | Other Derivative Acquisition | +50,000 | $115.44 | 50,000 |
| 12 Aug 2026 | Joseph Shulman | Chief Technology Officer | Automatic Disposition | -3,055 | $119.75 | 15,915 |
| 12 Aug 2026 | Joseph Shulman | Chief Technology Officer | Derivative Exercise and Sale | -2,024 | $119.75 | 15,915 |
| 12 Aug 2026 | Alastair Garfield | Chief Scientific Officer | Automatic Disposition | -7,763 | $119.17 | 2,295 |
| 12 Aug 2026 | Jennifer Lee | Executive VP & Head of North America | Automatic Disposition | -19,233 | $117.38 | – |
| 12 Aug 2026 | Jennifer Lee | Executive VP & Head of North America | Derivative Exercise and Sale | -56,601 | $117.38 | – |
| 11 Aug 2026 | Yann Mazabraud | Executive VP & Head of International | Automatic Disposition | -10,375 | $117.47 | 55,655 |
| 11 Aug 2026 | Yann Mazabraud | Executive VP & Head of International | Derivative Exercise and Sale | -46,625 | $117.47 | 55,655 |
| 10 Aug 2026 | Pamela Cramer | Former Chief Human Resources Officer | Intent to Sell (Form 144) | -11,406 | $115.48 | – |
| 9 Aug 2026 | Pamela Cramer | Former Chief Human Resources Officer | Intent to Sell (Form 144) | -3,520 | $115.63 | – |
| 30 Jun 2026 | Alastair Garfield | Chief Scientific Officer | Derivative Exercise and Sale | -2,150 | $110.41 | 10,058 |
| 30 Jun 2026 | Alastair Garfield | Chief Scientific Officer | Derivative Exercise and Retained | +2,295 | – | 10,058 |
| 23 Jun 2026 | Jennifer Good | Independent Director | Other Derivative Acquisition | +2,324 | – | 2,324 |
| 23 Jun 2026 | Jennifer Good | Independent Director | Other Derivative Acquisition | +3,691 | $107.55 | 3,691 |
| 23 Jun 2026 | David W. McGirr | Independent Director | Other Derivative Acquisition | +2,324 | – | 2,324 |
| 23 Jun 2026 | David W. McGirr | Independent Director | Other Derivative Acquisition | +3,691 | $107.55 | 3,691 |
数据来自Form 4/Form 144申报文件。负数为减持（出售、赠予或代扣税款股份），正数为增持。
空头持仓（按报告期）
| 报告日期 | 空头股数 | 占流通股比例 | 回补天数 |
|---|---|---|---|
| 15 Oct 2026 | 11,003,490 | 16.0% | 13.5 |
| 30 Sep 2026 | 10,767,698 | 15.6% | 14.1 |
| 15 Sep 2026 | 10,287,811 | 14.9% | 20.1 |
| 31 Aug 2026 | 10,303,031 | 15.0% | 21.9 |
| 14 Aug 2026 | 10,154,327 | 14.7% | 12.2 |
| 31 Jul 2026 | 9,440,417 | 13.8% | 16.2 |
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