股票 › QURE
uniQure基因治疗 QURE
美股市值排名 #2937
$21.70 +$0.69 (+3.28%)
休市 · Nov 7, 10:00 pm ET · 最新盘后价 $22.00 +1.38%
开盘$21.25
昨收$21.01
当日区间$21.10 – $21.93
成交量1.17M
市值$1.52B
市盈率（TTM）–
股息率–
股权结构与仓位
谁在持有、谁在做空，以及大资金的流向
机构持股比例97.0%-0.75 个百分点，较上季度
持仓机构数298-6 ，较上季度
内部人近期交易19次买入 / 31次卖出净卖出
空头持仓比例12.58% 占流通股回补天数 3.8 · 截至 15 Oct 2026
卖空成交量占比8.0%近5日成交量平均占比
卖空成交量占当日成交量比例
大单净流入，近20个交易日
大单买入减卖出的净额（美元）。该窗口期内：−$10.71M（11个净流入日，9个净流出日）。
按单量净流入，近20个交易日
超大单/大单近似机构级别交易；中单/小单近似散户级别交易。各档买入减卖出净额，按窗口期累计。
已披露的前五大股东合计持有30.5%的流通股。
最大股东
按投资者类型
过去6次双周报告中（31 Jul 2026至15 Oct 2026），空头持仓占流通股比例已从15.40%降至12.58%。
近期机构持仓变动
| 股东 | 类型 | 期间 | 持股变动 | 新持股比例 |
|---|---|---|---|---|
| J.P. Morgan Asset Management, Inc. | Mutual Fund | 2026/Q3 | +1,965,644 | 6.8% |
| RTW Investments, LP | Hedge Fund | 2026/Q3 | +1,355,216 | 5.7% |
| Jane Street Group, LLC | Private Company | 2026/Q3 | +974,488 | 2.3% |
| Boxer Capital Management, LLC | Hedge Fund | 2026/Q3 | +841,300 | 2.2% |
| Longaeva Partners L.P. | Mutual Fund | 2026/Q3 | +804,594 | 1.2% |
| MAK Capital One, LLC | Hedge Fund | 2026/Q3 | +790,846 | 1.8% |
| Avoro Capital Advisors LLC | Hedge Fund | 2026/Q3 | +768,182 | 9.7% |
| State Street Global Advisors | Mutual Fund | 2026/Q3 | +643,313 | 4.2% |
| Morgan Stanley | Public Company | 2026/Q3 | +609,161 | 1.1% |
| Point72 Asset Management, L.P. | Hedge Fund | 2026/Q3 | +606,212 | 0.9% |
| Kinetic Partners Management LP | VC/PE Fund | 2026/Q3 | +581,000 | 0.8% |
| Vestal Point Capital, LP | Hedge Fund | 2026/Q3 | +576,004 | 1.3% |
| Invesco Ltd. | Mutual Fund | 2026/Q3 | +535,119 | 0.8% |
| Gilder Gagnon Howe & Co. LLC | Mutual Fund | 2026/Q3 | +530,979 | 0.8% |
| Citadel Advisors LLC | Hedge Fund | 2026/Q3 | +505,773 | 1.3% |
按报告期列出的机构买卖动态，变动幅度从大到小排列。
内部人交易
| 日期 | 内部人 | 职位 | 交易类型 | 股数 | 价格 | 交易后持股 |
|---|---|---|---|---|---|---|
| 1 Jul 2026 | Matthew Kapusta | Chief Executive Officer | Derivative Exercise and Sale | -21,082 | $45.89 | 519,227 |
| 29 Jun 2026 | Jack Kaye | Independent Non-Executive Director | Derivative Exercise and Sale | -21,167 | $46.49 | 25,996 |
| 29 Jun 2026 | Walid Abi-Saab | Chief Medical Officer | Automatic Disposition | -20,000 | $46.40 | 148,235 |
| 29 Jun 2026 | Walid Abi-Saab | Chief Medical Officer | Derivative Exercise and Sale | -10,000 | $46.46 | 148,235 |
| 25 Jun 2026 | Walid Abi-Saab | Chief Medical Officer | Open Market Disposition | -1,434 | $46.86 | 168,235 |
| 24 Jun 2026 | Matthew Kapusta | Chief Executive Officer | Intent to Sell (Form 144) | -28,716 | $50.02 | – |
| 24 Jun 2026 | Matthew Kapusta | Chief Executive Officer | Derivative Exercise and Sale | -32,844 | $50.02 | 519,227 |
| 23 Jun 2026 | Matthew Kapusta | Chief Executive Officer | Automatic Disposition | -2,568 | $50.00 | 519,227 |
| 17 Jun 2026 | Matthew Kapusta | Chief Executive Officer | Intent to Sell (Form 144) | -41,671 | $46.38 | – |
| 17 Jun 2026 | Matthew Kapusta | Chief Executive Officer | Automatic Disposition | -138,863 | $50.00 | 335,195 |
| 17 Jun 2026 | Matthew Kapusta | Chief Executive Officer | Derivative Exercise and Sale | -67,237 | $50.00 | 335,195 |
| 16 Jun 2026 | Matthew Kapusta | Chief Executive Officer | Intent to Sell (Form 144) | -164,429 | $43.00 | – |
| 16 Jun 2026 | Jack Kaye | Independent Non-Executive Director | Derivative Exercise and Sale | -5,295 | $42.57 | 18,446 |
| 16 Jun 2026 | Madhavan Balachandran | Independent Non-Executive Director | Derivative Exercise and Sale | -11,685 | $47.08 | 43,254 |
| 14 Jun 2026 | Madhavan Balachandran | Independent Non-Executive Director | Derivative Exercise and Sale | -10,000 | $27.85 | 43,254 |
| 14 Jun 2026 | Jeannette Potts | Chief Legal & Compliance Officer and Corporate Secretary | Open Market Disposition | -5,237 | $27.67 | 58,013 |
| 10 Jun 2026 | Leonard Post | Independent Non-Executive Director | Open Market Disposition | -1,993 | $27.06 | 27,944 |
| 10 Jun 2026 | Jack Kaye | Independent Non-Executive Director | Open Market Disposition | -1,993 | $27.06 | 18,446 |
| 10 Jun 2026 | Madhavan Balachandran | Independent Non-Executive Director | Open Market Disposition | -1,993 | $27.06 | 35,704 |
| 10 Jun 2026 | Jeremy Springhorn | Independent Non-Executive Director | Open Market Disposition | -1,993 | $27.06 | 35,701 |
数据来自Form 4/Form 144申报文件。负数为减持（出售、赠予或代扣税款股份），正数为增持。
空头持仓（按报告期）
| 报告日期 | 空头股数 | 占流通股比例 | 回补天数 |
|---|---|---|---|
| 15 Oct 2026 | 8,726,589 | 12.6% | 3.8 |
| 30 Sep 2026 | 8,715,837 | 12.6% | 1.9 |
| 15 Sep 2026 | 9,920,512 | 14.3% | 8.1 |
| 31 Aug 2026 | 9,874,417 | 14.2% | 9.4 |
| 14 Aug 2026 | 10,770,406 | 15.5% | 9.8 |
| 31 Jul 2026 | 10,683,529 | 15.4% | 6.8 |
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