开盘$267.56
昨收$272.32
当日区间$265.55 – $276.41
成交量8.86M
市值$664.95B
市盈率（TTM）42.0
股息率1.91%
股权结构与仓位
谁在持有、谁在做空，以及大资金的流向
机构持股比例76.5%+0.29 个百分点，较上季度
持仓机构数5,363+30 ，较上季度
内部人近期交易27次买入 / 20次卖出净买入
空头持仓比例0.70% 占流通股回补天数 2.0 · 截至 15 Oct 2026
卖空成交量占比9.2%近5日成交量平均占比
卖空成交量占当日成交量比例
大单净流入，近20个交易日
大单买入减卖出的净额（美元）。该窗口期内：−$142.67M（8个净流入日，12个净流出日）。
按单量净流入，近20个交易日
超大单/大单近似机构级别交易；中单/小单近似散户级别交易。各档买入减卖出净额，按窗口期累计。
已披露的前五大股东合计持有26.9%的流通股。
最大股东
按投资者类型
过去6次双周报告中（31 Jul 2026至15 Oct 2026），空头持仓占流通股比例已从1.05%降至0.70%。
近期机构持仓变动
| 股东 | 类型 | 期间 | 持股变动 | 新持股比例 |
|---|---|---|---|---|
| Assenagon Asset Management S.A. | Mutual Fund | 2026/Q3 | +1,051,362 | 0.1% |
| T. Rowe Price Group, Inc. | Mutual Fund | 2026/Q3 | +6,508,457 | 1.0% |
| Fisher Investments | Mutual Fund | 2026/Q3 | +4,043,445 | 0.6% |
| Wellington Management Group | Mutual Fund | 2026/Q3 | +2,513,321 | 0.9% |
| Capital Research | Mutual Fund | 2026/Q3 | +2,336,969 | 1.1% |
| SG Americas Securities, LLC | Private Company | 2026/Q3 | +1,269,232 | 0.2% |
| Deutsche Asset & Wealth Management | Mutual Fund | 2026/Q3 | +1,222,179 | 0.6% |
| Citigroup Inc. | Public Company | 2026/Q3 | +1,092,689 | 0.2% |
| The Goldman Sachs Group, Inc. | Public Company | 2026/Q3 | +1,069,846 | 0.2% |
| Hudson River Trading LLC | Private Company | 2026/Q3 | +1,031,961 | 0.0% |
| Assenagon Asset Management S.A. | Mutual Fund | 2026/Q3 | +902,292 | 0.1% |
| AGF Management Limited | Mutual Fund | 2026/Q3 | +887,557 | 0.1% |
| Invesco Capital Management LLC | Mutual Fund | 2026/Q3 | +873,516 | 0.3% |
| TD Asset Management | Mutual Fund | 2026/Q3 | +870,065 | 0.2% |
| Vanguard Portfolio Management, LLC | Mutual Fund | 2026/Q3 | +856,380 | 2.7% |
按报告期列出的机构买卖动态，变动幅度从大到小排列。
内部人交易
| 日期 | 内部人 | 职位 | 交易类型 | 股数 | 价格 | 交易后持股 |
|---|---|---|---|---|---|---|
| 7 Sep 2026 | Marillyn Hewson | Lead Independent Director | Other Derivative Acquisition | +180 | – | 16,049 |
| 7 Sep 2026 | Eugene Woods | Independent Director | Other Derivative Acquisition | +135 | – | 6,579 |
| 7 Sep 2026 | Daniel Pinto | Director | Other Derivative Acquisition | +113 | – | 2,445 |
| 1 Sep 2026 | Timothy Schmid | Executive VP & Worldwide Chairman of MedTech | Derivative Exercise and Sale | -33,597 | $274.74 | 26,251 |
| 31 Aug 2026 | Tom Cavanaugh | Executive VP & Worldwide Chairman of Innovative Medicine | Initial Statement of Beneficial | +0 | – | 5,337 |
| 16 Aug 2026 | Jennifer Taubert | Former Executive VP & Worldwide Chairman of Innovative Medicine | Derivative Exercise and Sale | -15,000 | $263.36 | 194,451 |
| 12 Aug 2026 | Joaquin Duato | Chairperson & CEO | Derivative Exercise and Sale | -123,291 | $262.00 | 307,837 |
| 5 Aug 2026 | Elizabeth Forminard | Chief Legal Officer | Open Market Disposition | -6,574 | $255.93 | 16,994 |
| 5 Aug 2026 | Elizabeth Forminard | Chief Legal Officer | Derivative Exercise and Sale | -9,344 | $257.76 | 16,994 |
| 4 Aug 2026 | Joaquin Duato | Chairperson & CEO | Open Market Disposition | -48,480 | $258.74 | 307,837 |
| 19 Jul 2026 | Vanessa Broadhurst | Executive Vice President of Global Corporate Affairs | Derivative Exercise and Sale | -23,054 | $251.27 | 23,003 |
| 10 Jun 2026 | Kathryn Wengel | Executive VP and Chief Technical Operations & Risk Officer | Derivative Exercise and Sale | -10,000 | $241.15 | 114,659 |
| 8 Jun 2026 | Marillyn Hewson | Lead Independent Director | Other Derivative Acquisition | +214 | – | 15,792 |
| 8 Jun 2026 | Eugene Woods | Independent Director | Other Derivative Acquisition | +161 | – | 6,412 |
| 8 Jun 2026 | Daniel Pinto | Director | Other Derivative Acquisition | +134 | – | 2,321 |
| 30 Apr 2026 | John Reed | Executive Vice President of Innovative Medicine and R&D | Derivative Exercise and Sale | -11,002 | $229.85 | 24,911 |
| 30 Apr 2026 | John Reed | Executive Vice President of Innovative Medicine and R&D | Derivative Exercise and Retained | +14,253 | – | 24,911 |
| 22 Apr 2026 | John Morikis | Director | Other Derivative Acquisition | +1,540 | – | 1,540 |
| 22 Apr 2026 | Hubert Joly | Independent Director | Other Derivative Acquisition | +975 | – | 9,184 |
| 22 Apr 2026 | Marillyn Hewson | Lead Independent Director | Other Derivative Acquisition | +975 | – | 15,488 |
数据来自Form 4/Form 144申报文件。负数为减持（出售、赠予或代扣税款股份），正数为增持。
空头持仓（按报告期）
| 报告日期 | 空头股数 | 占流通股比例 | 回补天数 |
|---|---|---|---|
| 15 Oct 2026 | 16,766,729 | 0.7% | 2.0 |
| 30 Sep 2026 | 22,070,973 | 0.9% | 3.3 |
| 15 Sep 2026 | 21,188,522 | 0.9% | 3.7 |
| 31 Aug 2026 | 21,670,595 | 0.9% | 3.3 |
| 14 Aug 2026 | 21,591,738 | 0.9% | 3.3 |
| 31 Jul 2026 | 25,408,119 | 1.1% | 3.0 |
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