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艾昂尼斯制药 IONS

美股市值排名 #1818生物科技
$39.42 +$0.62 (+1.60%)
休市 · Nov 6, 8:10 pm ET · 最新盘后价 $39.20 -0.56%
开盘$39.02
昨收$38.80
当日区间$38.53 – $40.00
成交量2.91M
市值$6.55B
市盈率（TTM）–
股息率–

股权结构与仓位

谁在持有、谁在做空，以及大资金的流向

机构持股比例110.0%-0.43 个百分点，较上季度
持仓机构数605-19 ，较上季度
内部人近期交易28次买入 / 22次卖出净买入
ARK基金动态+100,241 股1笔近期交易 · 最近一次 20 Sep 2026
空头持仓比例12.43% 占流通股回补天数 7.7 · 截至 15 Oct 2026
卖空成交量占比15.1%近5日成交量平均占比

卖空成交量占当日成交量比例

6%13%21%29%Sep '26Oct '26Nov '26

大单净流入，近20个交易日

大单买入减卖出的净额（美元）。该窗口期内：−$70.29M（8个净流入日，12个净流出日）。

按单量净流入，近20个交易日

−$75.7M超大单+$5.4M大单+$7.2M中单−$1.9M小单

超大单/大单近似机构级别交易；中单/小单近似散户级别交易。各档买入减卖出净额，按窗口期累计。

已披露的前五大股东合计持有44.7%的流通股。

最大股东

  • FMR14.82%
  • Capital Research13.73%
  • BlackRock6.44%
  • Vanguard Capital Management, LLC4.98%
  • Vanguard Portfolio Management, LLC4.73%
  • Wellington Management Group4.60%
  • T. Rowe Price Group, Inc.4.30%
  • Two Sigma Investments, LP3.76%

按投资者类型

  • Mutual Fund88.33%
  • Hedge Fund11.75%
  • Public Company5.22%
  • VC/PE Fund1.80%
  • Government Pension Fund1.29%
  • Private Company1.10%
  • Individual/Insider0.78%
  • Insurance Company0.29%

过去6次双周报告中（31 Jul 2026至15 Oct 2026），空头持仓占流通股比例已从12.92%降至12.43%。

近期机构持仓变动

股东类型期间持股变动新持股比例
Royal Bank of Canada Public Company 2026/Q3 +2,567,204 1.7%
Capital Research Mutual Fund 2026/Q3 +1,315,542 13.7%
Barclays PLC Public Company 2026/Q3 +1,294,472 0.9%
Wellington Management Group Mutual Fund 2026/Q3 +1,259,599 4.6%
Alyeska Investment Group, L.P. Hedge Fund 2026/Q3 +944,766 0.9%
Polar Capital Holdings Plc Mutual Fund 2026/Q3 +624,510 0.9%
Artisan Partners Limited Partnership Mutual Fund 2026/Q3 +581,716 1.6%
Neuberger Berman Investment Advisers LLC Mutual Fund 2026/Q3 +525,489 0.4%
Macquarie Investment Management Business Trust Mutual Fund 2026/Q3 +515,111 0.8%
Delaware Management Company Mutual Fund 2026/Q3 +469,650 0.6%
The Goldman Sachs Group, Inc. Public Company 2026/Q3 +435,788 0.9%
Davern Capital Partners, LP Hedge Fund 2026/Q3 +411,806 0.5%
Two Sigma Investments, LP Hedge Fund 2026/Q3 +394,713 3.8%
Freestone Grove Partners LP Hedge Fund 2026/Q3 +339,967 0.2%
State Street Global Advisors Mutual Fund 2026/Q3 +339,284 2.6%

按报告期列出的机构买卖动态，变动幅度从大到小排列。

内部人交易

日期内部人职位交易类型股数价格交易后持股
15 Oct 2026 Shannon L. Devers Executive VP & Chief Human Resource Officer Intent to Sell (Form 144) -1,357 $44.00 –
15 Oct 2026 Eric Swayze Executive Vice President & Head of Research Derivative Exercise and Sale -53 $43.54 22,149
15 Oct 2026 Shannon L. Devers Executive VP & Chief Human Resource Officer Derivative Exercise and Sale -1,357 $43.54 17,811
14 Oct 2026 Eric Swayze Executive Vice President & Head of Research Derivative Exercise and Retained +72 – 22,149
14 Oct 2026 Shannon L. Devers Executive VP & Chief Human Resource Officer Derivative Exercise and Retained +1,463 – 17,811
30 Aug 2026 C. Bennett Chief Scientific Officer Other Acquisition +110 $51.31 75,128
30 Aug 2026 Brett Monia Chief Executive Officer Other Acquisition +98 $51.31 242,760
30 Aug 2026 Patrick O'Neil Executive VP, Chief Legal Officer, General Counsel & Corporate Secretary Other Acquisition +63 $51.31 59,205
30 Aug 2026 Brian Birchler Executive Vice President of Corporate & Development Operations Other Acquisition +58 $51.31 102,883
30 Jul 2026 Michael Hayden Independent Director Open Market Acquisition +20,000 $53.38 78,298
14 Jul 2026 Joan Herman Independent Director Derivative Exercise and Retained +5,220 – 51,306
14 Jul 2026 Spencer Berthelsen Independent Director Derivative Exercise and Retained +5,220 – 161,303
14 Jul 2026 Ludwig Hantson Director Other Derivative Acquisition +3,399 – 3,399
14 Jul 2026 Peter Reikes Director Other Derivative Acquisition +3,399 – 3,399
6 Jul 2026 C. Bennett Chief Scientific Officer Other Acquisition +15,000 – 75,018
6 Jul 2026 C. Bennett Chief Scientific Officer Automatic Disposition -20,536 $85.46 75,018
6 Jul 2026 C. Bennett Chief Scientific Officer Other Derivative Disposition -15,000 – 12,109
6 Jul 2026 Allene Diaz Independent Director Derivative Exercise and Sale -10,111 $85.42 3,811
6 Jul 2026 Holly Kordasiewicz Chief Development Officer Automatic Disposition -362 $84.30 22,096
30 Jun 2026 Joan Herman Independent Director Other Derivative Acquisition +2,301 – 7,521

数据来自Form 4/Form 144申报文件。负数为减持（出售、赠予或代扣税款股份），正数为增持。

空头持仓（按报告期）

报告日期空头股数占流通股比例回补天数
15 Oct 2026 20,653,026 12.4% 7.7
30 Sep 2026 22,508,744 13.5% 4.6
15 Sep 2026 20,890,252 12.6% 5.2
31 Aug 2026 20,924,638 12.6% 9.2
14 Aug 2026 20,909,181 12.6% 9.6
31 Jul 2026 21,466,123 12.9% 6.4

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