Dyne 制药 DYN

On March 20, 2025, Dyne Therapeutics, Inc. announced that its Board of Directors had appointed Erick Lucera as Chief Financial Officer and Treasurer of the Company, effective as of March 31, 2025. In addition, Mr. Lucera will serve as the Company's principal financial officer and principal accounting officer. Prior to his appointment as Chief Financial Officer and Treasurer of the Company, Mr. Lucera, age 57, served as the Chief Financial Officer of Editas Medicine, Inc., a biotechnology company, from May 2023 to March 2025. Prior to that, Mr. Lucera served as the Chief Financial Officer of AVEO Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, from January 2020 until its acquisition by LG Chem, Ltd. in March 2023. From August 2016 to January 2020, Mr. Lucera served as Chief Financial Officer of Valeritas Holdings, Inc., a commercial-stage medical technology company. Mr. Lucera has served on the boards of directors of Beyond Air, Inc., a public commercial-stage medical device and biopharmaceutical company, since August 2017 and SAB Biotherapeutics, Inc., a public clinical-stage biopharmaceutical company, since April 2023. He previously served on the board of directors of Bone Biologics Corporation, a public medical device company, from October 2021 until December 2023. Mr. Lucera holds a C.P.H. from Harvard University, an M.S. in finance from Boston College, an MBA from Indiana University, Bloomington, and a B.S. in accounting from the University of Delaware. Mr. Lucera currently holds a CFA designation.

John G. Cox, has served as our Chief Executive Officer and President and as a director of our company since March 2024. Previously, Mr. Cox served as the Chief Executive Officer and a member of the board of directors of Repertoire Immune Medicines, Inc., a biotechnology company, from January 2020 to November 2022. Prior to that, Mr. Cox served as the Executive Chairman of Torque Therapeutics, Inc., or Torque, a biotechnology company, from January 2019 until September 2019, and as the Chief Executive Officer of Torque from September 2019 until January 2020, when Torque merged with another company to form Repertoire Immune Medicines, Inc. From February 2017 to September 2018, Mr. Cox served as Chief Executive Officer of Bioverativ Inc., a biotechnology company, which was acquired by Sanofi S.A. in February 2018. From 2003 to February 2017, Mr. Cox served in various roles at Biogen Inc., a biopharmaceutical company. From May 2016 until February 2017, he led the process to spin-off Biogen Inc.'s hematology division into an independent company, which became Bioverativ Inc.; from 2015 to 2016, Mr. Cox served as Executive Vice President of Global Commercial, Pharmaceutical & Technical Operations; and from 2010 to 2015, Mr. Cox served as Executive Vice President of Pharmaceutical Operations & Technology. Mr. Cox has served as a member of the board of directors of Minovia Therapeutics Ltd., a biotechnology company, since 2019 and of Canopy-Immuno Therapeutics Ltd., a biotechnology company, since March 2023. Mr. Cox previously served as a member of the board of directors of Sigilon Therapeutics, Inc., a biotechnology company, from March 2019 to August 2023 and Repligen Corporation, a biotechnology company, from 2014 to February 2020. Mr. Cox holds a B.S. in biology from Arizona State University, an M.B.A. from the University of Michigan and an M.S. in cell biology from California State University.

Johanna Friedl-Naderer has served as our Chief Commercial Officer since September 2024. Prior to joining us, Ms. Friedl-Naderer served as Executive Vice President and Chief Operating Officer of Vir Biotechnology, Inc. in the field of infectious disease from March 2022 to March 2024. As president Europe, Canada & Partner Markets for Biogen Inc. from November 2019 to January 2022, she led her team to launch multiple specialty and rare disease products across 35 markets. During her more than 20-year tenure at Biogen, she held positions of increasing responsibility across a wide range of functions, building and leading teams in advancing access to medicines for the treatment of neurological conditions, including multiple sclerosis, spinal muscular atrophy, amyotrophic lateral sclerosis and Alzheimer's disease. Ms. Friedl-Naderer has also served on several boards including the European Federation of Pharmaceutical Industries & Associations.

Oxana Beskrovnaya, Ph.D. has served as our Chief Scientific Officer since June 2021. She previously served as our Senior Vice President, Head of Research from January 2020 to May 2021. Prior to joining us, Dr. Beskrovnaya served as head of musculoskeletal and renal research in Sanofi's rare disease and neurological unit from July 2011 to January 2020. Dr. Beskrovnaya is the author of numerous patents, invited reviews, editorials, book chapters and original research articles in major scientific journals. Dr. Beskrovnaya received her Ph.D. in genetics from Moscow Genetics Institute, followed by postdoctoral fellowship training in neuromuscular diseases at the Howard Hughes Medical Institute at the University of Iowa. On April 28, 2025, Dr. Beskrovnaya will transition to a new role as our Chief Innovation Officer and will no longer serve as one of our executive officers.

Vikram Karnani, has served as a director of our company since December 2025. Mr. Karnani has served as the President and Chief Executive Officer of Collegium Pharmaceutical, Inc. since November 2024. Previously, Mr. Karnani served as the Executive Vice President of Global Commercial and Medical Affairs, Rare Disease at Amgen Inc. from November 2023 to November 2024. Prior to its acquisition by Amgen Inc., Mr. Karnani served in various roles at Horizon Therapeutics from August 2014 to October 2023 including SVP, Rheumatology Business Unit, Chief Commercial Officer, and EVP and President of Global Commercial and Medical Affairs. Mr. Karnani serves on the board of directors of Briteseed LLC, a private company focused on smart medical devices, and Collegium Pharmaceutical, Inc. Mr. Karnani earned an M.B.A. from Northwestern University, M.S. in electrical engineering from Case Western Reserve University, and B.S. in electronic engineering from the University of Mumbai.

Brian Posner, has served as a director of our company since October 2025. Mr. Posner has served as the President of the Point Rider Group LLC since he founded the firm in 2008, as well as Point Rider Group (UK) Ltd since its inception in 2023. Prior to founding the Point Rider Group, he served as the President, CEO, co-Chief Investment Officer, and Portfolio Manager at ClearBridge Investments from 2005 to 2008, Managing Member, co-Founder, and Portfolio Manager at Hygrove Partners LLC from 2000 to 2005, Partner and Managing Director at Warburg Pincus LLC from 1997 to 1999, and Vice President and Portfolio Manager at Fidelity Investments from 1987 to 1996. Mr. Posner has served on the board of directors of Arch Capital Group Ltd. since 2010 and has served as a special advisor at V2M Capital since 2021. Additionally, Mr. Posner has held several previous board of director positions including Biogen from 2008 to 2022, AQR Capital Management from 2011 to 2022 (where he also served as Chair), Bioverativ, a Sanofi company, from 2017 to 2018 (where he also served as Chair), the Mutual Fund Store from 2013 to 2016, BG Medicine from 2010 to 2012, and Anadys Pharmaceuticals in 2011. Mr. Posner earned his B.A. from Northwestern University, where he is a Life Trustee and serves on the Advisory Board of its Center for the Study of Diversity and Democracy. He also received his M.B.A. from the University of Chicago Booth School of Business.

Jason Rhodes, has served as a director of our company since December 2017 and chairman of our board of directors since November 2018. Mr. Rhodes also served as our founding President and Chief Executive Officer from December 2017 to November 2018. Mr. Rhodes has been a partner at Atlas Venture since 2014. From 2010 to 2014, Mr. Rhodes was employed at Epizyme, Inc., a biotechnology company, where he most recently served as President and Chief Financial Officer. Mr. Rhodes serves as the chairman and a member of the board of directors of several private companies, and previously served as a director at Generation Bio Co. from October 2016 to February 2026, Replimune Group, Inc. from 2015 to 2022, Gemini Therapeutics, Inc. from 2016 to 2022 and Disarm Therapeutics, Inc. from 2016 to 2020. Mr. Rhodes earned a B.A. in history from Yale University and an M.B.A. from the Wharton School of the University of Pennsylvania.

Catherine Stehman-Breen, M.D. has served as a director of our company since June 2019. Dr. Stehman-Breen has served as the Chief Executive Officer of Winnow Therapeutics, Inc., a biotechnology company, since August 2025 and as a venture partner at F-Prime Capital since April 2025. Previously, Dr. Stehman-Breen served as the Chief Executive Officer and a member of the board of directors of Chroma Medicine, Inc., a biotechnology company, from December 2020 to December 2024. Prior to that, Dr. Stehman-Breen served as the Chief Development Officer of Obsidian Therapeutics, Inc., a biotechnology company, from July 2019 to December 2020, as an entrepreneur-in-residence at Atlas Venture, serving as Chief Medical Officer of our company from March 2018 to July 2019 and as Chief Medical Officer of Disarm Therapeutics, Inc., a biotechnology company, from April 2018 to July 2019. Additionally, Dr. Stehman-Breen also served as Chief Medical Officer of Sarepta Therapeutics, Inc. from March 2017 to December 2017 and as Vice President, Clinical Development and Regulatory Affairs at Regeneron Pharmaceuticals, Inc., a biotechnology company. Dr. Stehman-Breen serves as a member of the board of directors of Tenaya Therapeutics, Inc. and Winnow Therapeutics, Inc. Dr. Stehman-Breen previously served as a member of the board of directors of Generation Bio Co. from December 2017 to February 2026. Dr. Stehman-Breen earned a B.A. in biology and psychology from Colby College, an M.Sc. degree in epidemiology from the University of Washington, where she also conducted her residency and fellowship training, and an M.D. from the University of Chicago.

Carlo Incerti, M.D.has served as a director of our company since March 2022. Dr. Incerti has served as an operating partner at Forbion since January 2019. Previously, he served as Senior Vice President, Chief Medical Officer and Head of Global Medical Affairs at Sanofi Genzyme, a healthcare company, from May 2011 to December 2018. Prior to the acquisition of Genzyme Corporation, a biotechnology company, by Sanofi in 2011, Dr. Incerti served as Senior Vice President of Global Market Access at Genzyme from 2010 to 2011 and held a number of positions at Genzyme in their European headquarters in the Netherlands from 1993 to 2010. Dr. Incerti serves as a member of the board of directors at Azafaros B.V., Synox Therapeutics Ltd., Numab Therapeutics AG. and Sparrow Pharmaceuticals, Inc., and previously served as a director at MolMed SpA from 2016 to 2020, EryDel SpA from 2020 to 2023, Inversago Pharma, Inc. from 2020 to 2023, and Vectory B.V. from October 2020 to June 2024. Dr. Incerti is also a founding member of the International Rare Diseases Research Consortium. He received his medical degree from the University of Modena and Reggio Emilia in Italy.

Edward Hurwitz, has served as a director of our company since November 2018. Mr. Hurwitz has served as Managing Director of Precision BioVentures LLC since he founded the firm in 2013. Mr. Hurwitz was a Managing Director at MPM Capital from January 2017 until March 2023 and a Director at Alta Partners from 2002 through December 2014. Prior to joining Alta Partners, Mr. Hurwitz served as Senior Vice President and CFO of Affymetrix, Inc. from 1997 to 2002. Prior to his service at Affymetrix, Mr. Hurwitz was a biotechnology research analyst for Robertson Stephens & Company and Smith Barney Shearson and a lawyer at Cooley Godward LLP. Mr. Hurwitz serves as a member of the board of directors of MacroGenics, Inc. and several private companies, and previously served as a director at Applied Genetic Technologies Corporation from 2012 to 2022. Mr. Hurwitz earned his J.D. and M.B.A. degrees from the University of California, Berkeley, and his B.A. in molecular biology from Cornell University.

Debra is an accomplished R&D leader with more than 20 years of regulatory experience in biotech and the life sciences. She has reviewed and authored numerous successful INDs, CTAs, NDAs, MAAs and submissions for breakthrough, fast track, orphan drug and pediatric designations to advance innovative and data-driven science. Prior to joining Dyne, Debra led the regulatory organization at Sage Therapeutics, overseeing regulatory initiatives across a pipeline of products to address neurological and psychiatric disorders. During her time at Sage, she led the company through the approval of ZULRESSO (brexanolone), the first and only treatment specifically indicated for postpartum depression. Prior to Sage, Ms. Feldman held various regulatory roles focused on multiple therapeutic areas, including rare diseases. Debra holds a B.A. from University of Massachusetts, Amherst, a degree in nutritional science from Simmons College and an M.P.H. from Boston University.