开盘$171.54
昨收$171.78
当日区间$171.28 – $176.41
成交量2.05M
市值$49.27B
市盈率（TTM）34.5
股息率0.58%
股权结构与仓位
谁在持有、谁在做空，以及大资金的流向
机构持股比例94.6%+0.28 个百分点，较上季度
持仓机构数1,439+68 ，较上季度
内部人近期交易17次买入 / 28次卖出净卖出
空头持仓比例1.78% 占流通股回补天数 2.4 · 截至 15 Oct 2026
卖空成交量占比16.8%近5日成交量平均占比
卖空成交量占当日成交量比例
大单净流入，近20个交易日
大单买入减卖出的净额（美元）。该窗口期内：−$57.98M（8个净流入日，12个净流出日）。
按单量净流入，近20个交易日
超大单/大单近似机构级别交易；中单/小单近似散户级别交易。各档买入减卖出净额，按窗口期累计。
已披露的前五大股东合计持有29.4%的流通股。
最大股东
按投资者类型
过去6次双周报告中（31 Jul 2026至15 Oct 2026），空头持仓占流通股比例已从2.04%降至1.78%。
近期机构持仓变动
| 股东 | 类型 | 期间 | 持股变动 | 新持股比例 |
|---|---|---|---|---|
| BNY Mellon Asset Management | Mutual Fund | 2026/Q3 | +1,804,782 | 2.5% |
| FMR | Mutual Fund | 2026/Q3 | +4,127,368 | 1.6% |
| BNY Mellon Asset Management | Mutual Fund | 2026/Q3 | +2,324,313 | 1.8% |
| Glenview Capital Management, LLC | Hedge Fund | 2026/Q3 | +1,969,541 | 0.7% |
| First Trust Advisors L.P. | Mutual Fund | 2026/Q3 | +1,293,526 | 0.7% |
| The Goldman Sachs Group, Inc. | Public Company | 2026/Q3 | +1,096,726 | 0.8% |
| Deutsche Asset & Wealth Management | Mutual Fund | 2026/Q3 | +1,027,613 | 2.5% |
| Pictet Asset Management Limited | Mutual Fund | 2026/Q3 | +996,992 | 1.6% |
| Alyeska Investment Group, L.P. | Hedge Fund | 2026/Q3 | +814,971 | 0.3% |
| UBS Asset Management | Mutual Fund | 2026/Q3 | +701,368 | 1.5% |
| AQR Capital Management | Hedge Fund | 2026/Q3 | +625,500 | 1.3% |
| Invesco Capital Management LLC | Mutual Fund | 2026/Q3 | +544,925 | 0.9% |
| Los Angeles Capital Management LLC | Mutual Fund | 2026/Q3 | +476,186 | 0.2% |
| Arrowstreet Capital, Limited Partnership | Mutual Fund | 2026/Q3 | +405,172 | 0.7% |
| Eaton Vance Management | Mutual Fund | 2026/Q3 | +391,154 | 1.4% |
按报告期列出的机构买卖动态，变动幅度从大到小排列。
内部人交易
| 日期 | 内部人 | 职位 | 交易类型 | 股数 | 价格 | 交易后持股 |
|---|---|---|---|---|---|---|
| 7 Sep 2026 | Glenn Boehnlein | Independent Director | Other Acquisition | +817 | $146.85 | 852 |
| 3 Sep 2026 | G. Dolsten | Independent Director | Open Market Disposition | -634 | $151.38 | 4,924 |
| 3 Sep 2026 | Glenn Boehnlein | Independent Director | Initial Statement of Beneficial | +0 | – | 35 |
| 25 Jun 2026 | Jonah Kirkwood | Senior VP & Chief Commercial Officer of Commercial Organization | Sale to Issuer | -30 | $136.01 | 14,108 |
| 2 Jun 2026 | Padraig McDonnell | Chief Executive Officer | Sale to Issuer | -418 | $137.40 | 65,842 |
| 1 Jun 2026 | Tim Downs | Vice President | Initial Statement of Beneficial | +0 | – | 8,872 |
| 28 May 2026 | G. Dolsten | Independent Director | Open Market Disposition | -1,600 | $135.42 | 5,548 |
| 18 May 2026 | Michael Buckner | Chief Legal Officer | Other Acquisition | +8,872 | – | 8,872 |
| 7 May 2026 | Simon May | Senior VP and President of Life Sciences & Diagnostics Markets Group | Sale to Issuer | -368 | $115.62 | 2,528 |
| 3 May 2026 | Michael Buckner | Chief Legal Officer | Initial Statement of Beneficial | +0 | – | 15 |
| 30 Mar 2026 | Meghan Henson | Chief Human Resources Officer | Sale to Issuer | -153 | $113.98 | 1,522 |
| 18 Mar 2026 | Otis Brawley | Independent Director | Other Acquisition | +3,046 | $111.75 | 13,874 |
| 18 Mar 2026 | George Scangos | Independent Director | Other Acquisition | +3,215 | $111.75 | 23,857 |
| 18 Mar 2026 | Dow Wilson | Independent Chairperson | Other Acquisition | +2,158 | $111.75 | 20,369 |
| 18 Mar 2026 | Boon Hwee Koh | Former Independent Non-Executive Chairperson | Sale to Issuer | -648 | $111.75 | 63,184 |
| 18 Mar 2026 | Boon Hwee Koh | Former Independent Non-Executive Chairperson | Other Acquisition | +2,158 | $111.75 | 63,184 |
| 18 Mar 2026 | Pascal Claude Soriot | Independent Director | Sale to Issuer | -648 | $111.75 | 2,683 |
| 18 Mar 2026 | Pascal Claude Soriot | Independent Director | Other Acquisition | +2,158 | $111.75 | 2,683 |
| 18 Mar 2026 | Daniel Podolsky | Independent Director | Other Acquisition | +2,158 | $111.75 | 38,180 |
| 18 Mar 2026 | Judy L. Brown | Independent Director | Other Acquisition | +2,158 | $111.75 | 3,835 |
数据来自Form 4/Form 144申报文件。负数为减持（出售、赠予或代扣税款股份），正数为增持。
空头持仓（按报告期）
| 报告日期 | 空头股数 | 占流通股比例 | 回补天数 |
|---|---|---|---|
| 15 Oct 2026 | 5,025,670 | 1.8% | 2.4 |
| 30 Sep 2026 | 5,240,309 | 1.9% | 1.8 |
| 15 Sep 2026 | 5,078,629 | 1.8% | 2.5 |
| 31 Aug 2026 | 5,677,007 | 2.0% | 2.1 |
| 14 Aug 2026 | 5,170,553 | 1.8% | 3.8 |
| 31 Jul 2026 | 5,749,623 | 2.0% | 2.5 |
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