Vertex Pharmaceuticals VRTX

US equityMarket cap rank #116Biotechnology Gene Editing

$521.79

+$5.45 (+1.05%)

Market open · Sep 24, 2:00 pm ET

After hours $517.00 +0.13%

Open$515.56

Prev close$516.34

Day range$515.30 – $528.89

Volume376.3K

Market cap$132.25B

P/E (TTM)30.4

Dividend yield–

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership97.2%-0.07 pts vs. prior quarter

Institutions holding2,104-6 vs. prior quarter

Insider trades (recent)9 buys / 11 sellsNet selling

Short interest1.84% of floatDays to cover 4.5 · as of 31 Aug 2026

Short-sale volume share18.3%5-day average of daily volume

Net of large-order buying minus selling, in USD. Over this window: +$72.81M (15 inflow days, 5 outflow days).

Institutional holders2,104

Institutional ownership97.2%

Total transactions24

Bought9

Sold11

Report date	Shares short	% of float	Days to cover
31 Aug 2026	4,659,749	1.8%	4.5
14 Aug 2026	4,146,973	1.6%	3.1
31 Jul 2026	3,942,936	1.6%	3.0
15 Jul 2026	4,986,691	2.0%	3.1
30 Jun 2026	4,938,472	1.9%	2.0
15 Jun 2026	4,616,968	1.8%	3.8