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Vertex Pharmaceuticals VRTX

US equityMarket cap rank #117BiotechnologyGene Editing
$520.94
+$4.60 (+0.89%)
Market open · Sep 24, 1:10 pm ET
After hours $517.00 +0.13%
Open$515.56
Prev close$516.34
Day range$515.30 – $528.89
Volume332.9K
Market cap$132.04B
P/E (TTM)30.3
Dividend yield

Price chart

Daily bars for up to one year, weekly bars for the 5-year view. Averages are 50/200 trading days (10/40 weeks on the 5-year view).

VRTX at a glance

Vertex Pharmaceuticals (VRTX) is trading at $520.94, up 0.89% on the day. Its market value of $132.04B makes it the 117th largest of the 300 companies we follow.

The 52-week range is $384.39 to $560.25. Today's price is about 78% of the way from the low to the high. Holders are ahead 38.3% over twelve months, and up 9.6% across the last three months.

On the chart it holds above both the 50-day ($512.70) and 200-day ($471.12) moving averages; RSI is 50, and the last 30 sessions moved at roughly 26% annualized volatility.

Revenue for the quarter ended Jun 2026 was $3.33B, up 12.5% from a year earlier, with $1.10B of net profit (a 35.0% margin).

Buyers are paying 30.3 times trailing earnings. The median for its industry group is 34.0.

24 analysts follow the stock and the average call is "buy". The mean target, $579.00, sits 11.1% over where the stock trades.

This summary is put together from the numbers on the page and updates when they do. It describes the data; it is not a forecast or a recommendation.

Vertex Pharmaceuticals: the business

Vertex Pharmaceuticals makes cystic fibrosis treatments and is developing pain, kidney and diabetes therapies.

What tends to move it. Its cystic fibrosis sales are a steady base, and the market focuses on the Journavx pain drug and the pipeline.

Written by hand by the BeStock desk and revised when a business changes. See how we work. Spot something out of date? Tell us.

Performance

Price return over each window, from adjusted daily and weekly closes

1 day
+0.9%
1 week
+1.5%
1 month
-4.9%
3 months
+9.6%
6 months
+16.1%
Year to date
+14.9%
1 year
+38.3%
Day range
$515.30$528.89
52-week range
$384.39$560.25

Technical signals

Full technicals →
Trend readLeaning bullish

4 bullish · 3 bearish of 7 signals

IndicatorValueSignal
Price vs 20-day average-1.6%Bearish
Price vs 50-day average+1.6%Bullish
Price vs 200-day average+10.6%Bullish
50-day vs 200-day50d above 200dBullish
RSI (14)50.1Bullish
MACD (12,26,9)-1.97Bearish
Bollinger band position37%Bearish

Standard indicator readings worked out from daily closes. They describe how the price has behaved, not where it is going.

Key statistics

Bid / Ask$520.64 / $521.22
Average price today$522.86
Volume332.9KAvg (90d) 1.40M
Turnover$174.05M
Turnover rate0.13%of shares outstanding
Volume ratio0.43vs. recent average pace
Day amplitude2.63%
Market cap$132.04B
Float market cap$131.63B
Shares outstanding252.68M
EPS (TTM)$15.32
P/E (TTM)30.34
P/B6.52
Book value / share$79.89
Earnings yield0.21%
Net profit (TTM)$3.88B
Net assets$20.25B
30-day volatility25.7%annualized
Avg daily range (ATR)2.27%of price, 14 days
Max drawdown (1y)-15.2%-6.6% from 1y peak

Quote as of Sep 24, 2026 1:10 pm ET. Prices can lag the live tape. This is background information, not a recommendation.

How VRTX ranks on BeStock

Market value#117 of 300
P/E (cheapest = 1)#187 of 283
Closeness to 52-week high#61 of 300
Dollar volume today#176 of 300

Ranks are among the 300 or so U.S.-listed stocks BeStock covers, recalculated whenever prices refresh. A row is left out when the measure does not apply, such as yield for a stock that pays no dividend.

Latest reported quarter: Q2, ended Jun 2026

Revenue$3.33B+12.5% YoY
Operating profit$1.27B+9.9% YoY
Net profit$1.10B+6.5% YoY
Diluted EPS$4.31+8.0% YoY
Free cash flow$1.01B+9.3% YoY
Operating cash flow$1.13B

Revenue, last 8 quarters

$2.8BSep '24$2.9BDec '24$2.8BMar '25$3.0BJun '25$3.1BSep '25$3.2BDec '25$3.0BMar '26$3.3BJun '26

Net profit, last 8 quarters

$1.0BSep '24$913.0MDec '24$646.3MMar '25$1.0BJun '25$1.1BSep '25$1.2BDec '25$1.0BMar '26$1.1BJun '26

Profitability & balance sheet

Gross margin86.0%
Operating margin37.9%
Net margin35.0%
Return on equity23.5%
Return on assets17.1%
Return on invested capital19.5%
Current ratio3.19
Liabilities / assets26.2%
Cash & investments$7.85B
Total debt$1.98B
Net cash (debt)$5.87B
Free cash flow / sales30.2%

Where the revenue comes from

Quarter 2026/Q2

By business line

  • TRIKAFTA/KAFTRIO$2.50B 74.9%
  • ALYFTREK$573.60M 17.2%
  • Other cystic fibrosis (CF) products$137.10M 4.1%
  • CASGEVY$76.40M 2.3%
  • JOURNAVX$49.60M 1.5%
Average move on report day±4.9%last 15 reports
Closed higher6 of 1540% of the time
Best reaction+9.0%
Worst reaction-20.6%

Stock move on the day after each report

+5.7%2024/Q3-3.1%2024/Q4-10.0%2025/Q1-20.6%2025/Q2-1.0%2025/Q3+5.7%2025/Q4-1.3%2026/Q1+1.7%2026/Q2

"Implied move" is the size of move the options market was pricing ahead of the report. Move is the stock’s change on the first session after the release.

Valuation

Multiples measured against the stock's own five-year history

Valuation detail →
Price / earnings29.9x
CheapRich

Above its usual level · 79th percentile, 5-year average -19.3x

#2069 of 2975 stocks by PE (1 = cheapest)

Price / book6.4x
CheapRich

Above its usual level · 61st percentile, 5-year average 6.4x

#4541 of 5302 stocks by PB (1 = cheapest)

Price / sales10.3x
CheapRich

Above its usual level · 68th percentile, 5-year average 9.8x

#4414 of 5141 stocks by PS (1 = cheapest)

P/E over five years

-290x-159x-27x105xSep '21Mar '24Sep '26

Dashed line is the 5-year average; the shaded band is one standard deviation either side.

Morningstar fair value estimate

Fair value$450.00
Price vs. fair value+15.8%Trading above the estimate
Star rating★★☆☆☆
Economic moatNarrow
UncertaintyHigh

Analyst view

All ratings →
ConsensusBuy
Analysts24
Average target$579.00+11.1% vs. price
  • Buy 88%
  • Hold 8%
  • Sell 4%
Low $350.00Now $520.94Avg $579.00High $672.00

Latest rating actions

  • 16 Sep 2026ScotiabankBUY · PT $558.00
  • 14 Sep 2026Morgan StanleyBUY · PT $665.00
  • 11 Sep 2026J.P. MorganBUY · PT $560.00
  • 2 Sep 2026CitiBUY · PT $585.00
  • 1 Sep 2026Morgan StanleyBUY · PT $665.00

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Ownership detail →
Institutional ownership97.2%-0.07 pts vs. prior quarter
Institutions holding2,104-6 vs. prior quarter
Insider trades (recent)9 buys / 11 sellsNet selling
Short interest1.84% of floatDays to cover 4.5 · as of 31 Aug 2026
Short-sale volume share18.3%5-day average of daily volume

Short-sale volume as % of daily volume

12%15%18%22%Aug '26Sep '26Sep '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: +$72.81M (15 inflow days, 5 outflow days).

Latest headlines

More news →
  • News On Crinetics Pharmaceuticals Inc. (CRNX) Now Under VRTXDow Jones · 2 Sep 2026
  • Morgan Stanley Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Raises Target Price to $665Market news · 2 Sep 2026
  • Analysts Offer Insights on Healthcare Companies: Vertex Pharmaceuticals (VRTX), Alumis Inc. (ALMS) and Medtronic (MDT)TipRanks · 2 Sep 2026
  • Citi Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Maintains Target Price $585Market news · 2 Sep 2026
  • Scotiabank Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Maintains Target Price $558Market news · 16 Sep 2026
  • Morgan Stanley Maintains Vertex Pharmaceuticals(VRTX.US) With Buy Rating, Maintains Target Price $665Market news · 15 Sep 2026

VRTX stock: common questions

What is VRTX's latest share price?

$520.94 is the latest print for VRTX, a move of +0.89% against yesterday's close of $516.34. Today's low and high so far: $515.30 and $528.89.

How large is Vertex Pharmaceuticals by market value?

Equity value comes to $132.04B at the current price. By that measure it is number 117 of the 300 names in our coverage.

How is Vertex Pharmaceuticals valued against its profits?

Buyers pay 30.3 times the last twelve months of profit (EPS $15.32).

Where does VRTX sit in its 52-week range?

The year's floor is $384.39 and the ceiling $560.25. Shares are 7.0% away from that ceiling.

Does VRTX send cash back through a dividend?

Our data shows no dividend paid by Vertex Pharmaceuticals over the trailing twelve months.

What is the analyst view on Vertex Pharmaceuticals?

Of 24 analysts, 88% say buy, 8% hold and 4% sell. Price targets average $579.00, with the most cautious at $350.00 and the most optimistic at $672.00.

What does Vertex Pharmaceuticals do?

Vertex Pharmaceuticals makes cystic fibrosis treatments and is developing pain, kidney and diabetes therapies.

BeStock publishes market data and analysis for information only. Nothing here is investment advice or a solicitation to buy or sell any security. Quotes may be delayed and figures can contain errors; check primary sources before you trade. How we source and calculate these pages.

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