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Spyre Therapeutics SYRE

US equityMarket cap rank #1637
$92.72 −$0.47 (-0.50%)
Market closed · Oct 5, 9:30 pm ET · Last extended-hours $89.00 -4.01%
Open$93.02
Prev close$93.19
Day range$89.49 – $95.01
Volume642.9K
Market cap$8.18B
P/E (TTM)–
Dividend yield–

Price chart

Daily bars for up to one year, weekly bars for the 5-year view. Averages are 50/200 trading days (10/40 weeks on the 5-year view). Triangles mark past earnings reports, colored by that day’s move; ticks mark ex-dividend dates — hover either for the date. Volume is the shaded bars under the price; switch on RSI or MACD above for a full-history oscillator panel, not just today’s reading.

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SYRE at a glance

SYRE last changed hands at $92.72 (down 0.50%). At $8.18B, Spyre Therapeutics is ranked #1637 by size among the 2132 stocks on BeStock.

The 52-week range is $18.12 to $110.18. Today's price is about 81% of the way from the low to the high. Holders are ahead 456.2% over twelve months, but down 1.6% across the last three months.

Price is below the 50-day average ($95.79) but above the 200-day ($67.92); RSI is 53, and the last 30 sessions moved at roughly 52% annualized volatility.

This summary is put together from the numbers on the page and updates when they do. It describes the data; it is not a forecast or a recommendation.

SYRE is not currently one of the 10 holdings in BeStock Momentum, our rules-based momentum strategy.

Since 2021-01-04, the strategy has returned 389% (231.1% for the equal-weight average of BeStock’s coverage over the same stretch). Holdings can change any trading day, not just on a fixed schedule. Backtested performance, updated weekly — not a guarantee of future results, and not a BeStock recommendation.

Performance

Price return over each window, from adjusted daily and weekly closes

1 day
-0.5%
1 week
+8.1%
1 month
+6.3%
3 months
-1.6%
6 months
+89.3%
Year to date
+183.0%
1 year
+456.2%
Day range
$89.49$95.01
52-week range
$18.12$110.18

Technical signals

Full technicals →
Trend readStrong uptrend

6 bullish · 1 bearish of 7 signals

IndicatorValueSignal
Price vs 20-day average+3.4%Bullish
Price vs 50-day average-3.2%Bearish
Price vs 200-day average+36.5%Bullish
50-day vs 200-day50d above 200dBullish
RSI (14)53.3Bullish
MACD (12,26,9)-1.22Bullish
Bollinger band position80%Bullish

Standard indicator readings worked out from daily closes. They describe how the price has behaved, not where it is going.

Key statistics

Bid / Ask$88.74 / $90.00
Average price today$92.05
Volume642.9KAvg (90d) 1.29M
Turnover$59.17M
Turnover rate0.78%of shares outstanding
Volume ratio0.45vs. recent average pace
Day amplitude5.92%
Market cap$8.18B
Float market cap$7.62B
Shares outstanding82.15M
EPS (TTM)-$1.98
P/B8.56
Book value / share$10.83
Earnings yield-0.18%
Net profit (TTM)-$174.58M
Net assets$954.75M
30-day volatility52.0%annualized
Avg daily range (ATR)5.09%of price, 14 days
Max drawdown (1y)-22.2%-14.9% from 1y peak

Quote as of Oct 5, 2026 9:30 pm ET. Prices can lag the live tape. This is background information, not a recommendation.

How SYRE ranks on BeStock

Market value#1637 of 2132
Closeness to 52-week high#971 of 2131
Dollar volume today#1122 of 2132

Ranks are among the 2,132 or so U.S.-listed stocks BeStock covers, recalculated whenever prices refresh. A tile is left out when the measure does not apply, such as yield for a stock that pays no dividend.

SYRE stock: common questions

Where is SYRE trading right now?

$92.72 is the latest print for SYRE, a move of -0.50% against yesterday's close of $93.19. Today's low and high so far: $89.49 and $95.01.

How big is Spyre Therapeutics?

Equity value comes to $8.18B at the current price. By that measure it is number 1637 of the 2132 names in our coverage.

Where does SYRE sit in its 52-week range?

The year's floor is $18.12 and the ceiling $110.18. Shares are 15.8% away from that ceiling.

Does SYRE send cash back through a dividend?

Our data shows no dividend paid by Spyre Therapeutics over the trailing twelve months.

BeStock publishes market data and analysis for information only. Nothing here is investment advice or a solicitation to buy or sell any security, and none of it is tailored to your financial situation, goals, or risk tolerance. Quotes may be delayed and figures can contain errors; check primary sources before you trade. How we source and calculate these pages.

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