Regeneron Pharmaceuticals REGN
Ownership & positioning
Who holds it, who is betting against it, and where the big money is moving
Short-sale volume as % of daily volume
Large-order net flow, last 20 sessions
Net of large-order buying minus selling, in USD. Over this window: −$26.33M (5 inflow days, 15 outflow days).
Net flow by order size, last 20 sessions
Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.
The five largest holders on file together own 29.1% of shares outstanding.
Largest holders
By investor type
Reported short interest has fallen from 3.29% to 2.07% of float over the last 6 biweekly reports (31 Jul 2026 to 15 Oct 2026).
Recent institutional activity
| Holder | Type | Period | Share change | New stake |
|---|---|---|---|---|
| Amundi Luxembourg S.A. | Mutual Fund | 2026/Q3 | +147,438 | 0.2% |
| Amundi Luxembourg S.A. | Mutual Fund | 2026/Q3 | +145,950 | 0.2% |
| Vanguard Portfolio Management, LLC | Mutual Fund | 2026/Q3 | +1,454,539 | 3.2% |
| Dodge & Cox | Mutual Fund | 2026/Q3 | +412,899 | 4.9% |
| Millennium Management LLC | Hedge Fund | 2026/Q3 | +355,691 | 0.5% |
| SG Americas Securities, LLC | Private Company | 2026/Q3 | +269,425 | 0.4% |
| Nordea Investment Management AB | Mutual Fund | 2026/Q3 | +269,157 | 0.4% |
| Arrowstreet Capital, Limited Partnership | Mutual Fund | 2026/Q3 | +222,114 | 0.4% |
| First Trust Advisors L.P. | Mutual Fund | 2026/Q3 | +200,277 | 0.5% |
| J.P. Morgan Mansart Management Limited | Mutual Fund | 2026/Q3 | +192,536 | 0.2% |
| State Street Global Advisors | Mutual Fund | 2026/Q3 | +170,210 | 4.8% |
| BlackRock | Mutual Fund | 2026/Q3 | +165,771 | 9.1% |
| Citigroup Inc. | Public Company | 2026/Q3 | +161,946 | 0.3% |
| Invesco Capital Management LLC | Mutual Fund | 2026/Q3 | +154,952 | 3.2% |
| Susquehanna International Group, LLP | Private Company | 2026/Q3 | +149,599 | 0.2% |
Institutional buy/sell activity by reporting period, largest moves first.
Insider transactions
| Date | Insider | Title | Transaction | Shares | Price | Held after |
|---|---|---|---|---|---|---|
| 13 Oct 2026 | Andrew Murphy | Executive VP of Research & Co-Chief Scientific Officer | Intent to Sell (Form 144) | -4,147 | $772.70 | – |
| 13 Oct 2026 | Andrew Murphy | Executive VP of Research & Co-Chief Scientific Officer | Derivative Exercise and Sale | -17,000 | $781.47 | 52,247 |
| 2 Sep 2026 | Marion McCourt | Executive Vice President of Commercial | Intent to Sell (Form 144) | -1,131 | $857.00 | – |
| 2 Sep 2026 | Marion McCourt | Executive Vice President of Commercial | Automatic Disposition | -2,346 | $857.39 | 12,222 |
| 1 Sep 2026 | Marion McCourt | Executive Vice President of Commercial | Intent to Sell (Form 144) | -1,215 | $850.00 | – |
| 1 Sep 2026 | Kathryn Guarini | Independent Director | Derivative Exercise and Sale | -400 | $850.00 | 603 |
| 18 Aug 2026 | Joseph LaRosa | General Counsel | Derivative Exercise and Sale | -9,019 | $830.15 | 45,595 |
| 18 Aug 2026 | Joseph LaRosa | General Counsel | Derivative Exercise and Retained | +3,263 | $381.92 | 45,595 |
| 17 Aug 2026 | Christopher Fenimore | Chief Financial Officer | Derivative Exercise and Sale | -4,599 | $813.47 | 23,505 |
| 17 Aug 2026 | Christopher Fenimore | Chief Financial Officer | Derivative Exercise and Retained | +1,684 | $381.92 | 23,505 |
| 9 Aug 2026 | Huda Zoghbi | Independent Director | Derivative Exercise and Sale | -800 | $800.00 | 1,703 |
| 9 Aug 2026 | Kathryn Guarini | Independent Director | Derivative Exercise and Sale | -400 | $800.00 | 603 |
| 1 Jul 2026 | Arthur Ryan | Former Independent Director | Automatic Disposition | -200 | $650.15 | 15,600 |
| 30 Apr 2026 | Arthur Ryan | Former Independent Director | Open Market Disposition | -100 | $714.13 | 15,800 |
| 31 Mar 2026 | Arthur Ryan | Former Independent Director | Automatic Disposition | -100 | $779.71 | 15,900 |
| 1 Mar 2026 | Arthur Ryan | Former Independent Director | Automatic Disposition | -100 | $789.28 | 16,000 |
| 18 Feb 2026 | Huda Zoghbi | Independent Director | Derivative Exercise and Sale | -1,638 | $790.00 | – |
| 8 Feb 2026 | Arthur Ryan | Former Independent Director | Automatic Disposition | -100 | $787.82 | 16,100 |
| 8 Feb 2026 | Jason Pitofsky | Senior Vice President | Automatic Disposition | -1,036 | $785.72 | 4,482 |
| 8 Feb 2026 | Jason Pitofsky | Senior Vice President | Derivative Exercise and Sale | -1,000 | $778.35 | 4,482 |
From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.
Short interest, by report
| Report date | Shares short | % of float | Days to cover |
|---|---|---|---|
| 15 Oct 2026 | 2,134,934 | 2.1% | 3.2 |
| 30 Sep 2026 | 2,150,303 | 2.1% | 2.5 |
| 15 Sep 2026 | 2,526,446 | 2.5% | 4.4 |
| 31 Aug 2026 | 2,552,029 | 2.5% | 3.9 |
| 14 Aug 2026 | 2,396,152 | 2.3% | 3.2 |
| 31 Jul 2026 | 3,385,841 | 3.3% | 3.9 |
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