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Regeneron Pharmaceuticals REGN

US equityMarket cap rank #226BiotechnologyInfectious Disease
$904.35 +$1.45 (+0.16%)
Market closed · Nov 7, 9:50 pm ET · Last extended-hours $900.00 -0.48%
Open$887.22
Prev close$902.90
Day range$887.04 – $911.64
Volume1.12M
Market cap$93.55B
P/E (TTM)20.0
Dividend yield0.41%

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership93.1%-0.60 pts vs. prior quarter
Institutions holding1,751+77 vs. prior quarter
Insider trades (recent)27 buys / 23 sellsNet buying
Short interest2.07% of floatDays to cover 3.2 · as of 15 Oct 2026
Short-sale volume share10.1%5-day average of daily volume

Short-sale volume as % of daily volume

5%9%13%17%Sep '26Oct '26Nov '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: −$26.33M (5 inflow days, 15 outflow days).

Net flow by order size, last 20 sessions

−$21.1MSuper−$5.2MBig+$13.1MMid+$75.6MSmall

Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.

The five largest holders on file together own 29.1% of shares outstanding.

Largest holders

  • BlackRock9.08%
  • Vanguard Capital Management, LLC7.17%
  • Dodge & Cox4.85%
  • State Street Global Advisors4.82%
  • Invesco Capital Management LLC3.23%
  • Vanguard Portfolio Management, LLC3.16%
  • J.P. Morgan Asset Management, Inc.3.15%
  • Geode Capital Management, LLC2.62%

By investor type

  • Mutual Fund77.94%
  • Hedge Fund4.59%
  • Public Company3.94%
  • Individual/Insider3.80%
  • Government Pension Fund2.54%
  • Private Company1.84%
  • Sovereign Wealth Fund1.26%
  • Insurance Company0.42%

Reported short interest has fallen from 3.29% to 2.07% of float over the last 6 biweekly reports (31 Jul 2026 to 15 Oct 2026).

Recent institutional activity

HolderTypePeriodShare changeNew stake
Amundi Luxembourg S.A. Mutual Fund 2026/Q3 +147,438 0.2%
Amundi Luxembourg S.A. Mutual Fund 2026/Q3 +145,950 0.2%
Vanguard Portfolio Management, LLC Mutual Fund 2026/Q3 +1,454,539 3.2%
Dodge & Cox Mutual Fund 2026/Q3 +412,899 4.9%
Millennium Management LLC Hedge Fund 2026/Q3 +355,691 0.5%
SG Americas Securities, LLC Private Company 2026/Q3 +269,425 0.4%
Nordea Investment Management AB Mutual Fund 2026/Q3 +269,157 0.4%
Arrowstreet Capital, Limited Partnership Mutual Fund 2026/Q3 +222,114 0.4%
First Trust Advisors L.P. Mutual Fund 2026/Q3 +200,277 0.5%
J.P. Morgan Mansart Management Limited Mutual Fund 2026/Q3 +192,536 0.2%
State Street Global Advisors Mutual Fund 2026/Q3 +170,210 4.8%
BlackRock Mutual Fund 2026/Q3 +165,771 9.1%
Citigroup Inc. Public Company 2026/Q3 +161,946 0.3%
Invesco Capital Management LLC Mutual Fund 2026/Q3 +154,952 3.2%
Susquehanna International Group, LLP Private Company 2026/Q3 +149,599 0.2%

Institutional buy/sell activity by reporting period, largest moves first.

Insider transactions

DateInsiderTitleTransactionSharesPriceHeld after
13 Oct 2026 Andrew Murphy Executive VP of Research & Co-Chief Scientific Officer Intent to Sell (Form 144) -4,147 $772.70 –
13 Oct 2026 Andrew Murphy Executive VP of Research & Co-Chief Scientific Officer Derivative Exercise and Sale -17,000 $781.47 52,247
2 Sep 2026 Marion McCourt Executive Vice President of Commercial Intent to Sell (Form 144) -1,131 $857.00 –
2 Sep 2026 Marion McCourt Executive Vice President of Commercial Automatic Disposition -2,346 $857.39 12,222
1 Sep 2026 Marion McCourt Executive Vice President of Commercial Intent to Sell (Form 144) -1,215 $850.00 –
1 Sep 2026 Kathryn Guarini Independent Director Derivative Exercise and Sale -400 $850.00 603
18 Aug 2026 Joseph LaRosa General Counsel Derivative Exercise and Sale -9,019 $830.15 45,595
18 Aug 2026 Joseph LaRosa General Counsel Derivative Exercise and Retained +3,263 $381.92 45,595
17 Aug 2026 Christopher Fenimore Chief Financial Officer Derivative Exercise and Sale -4,599 $813.47 23,505
17 Aug 2026 Christopher Fenimore Chief Financial Officer Derivative Exercise and Retained +1,684 $381.92 23,505
9 Aug 2026 Huda Zoghbi Independent Director Derivative Exercise and Sale -800 $800.00 1,703
9 Aug 2026 Kathryn Guarini Independent Director Derivative Exercise and Sale -400 $800.00 603
1 Jul 2026 Arthur Ryan Former Independent Director Automatic Disposition -200 $650.15 15,600
30 Apr 2026 Arthur Ryan Former Independent Director Open Market Disposition -100 $714.13 15,800
31 Mar 2026 Arthur Ryan Former Independent Director Automatic Disposition -100 $779.71 15,900
1 Mar 2026 Arthur Ryan Former Independent Director Automatic Disposition -100 $789.28 16,000
18 Feb 2026 Huda Zoghbi Independent Director Derivative Exercise and Sale -1,638 $790.00 –
8 Feb 2026 Arthur Ryan Former Independent Director Automatic Disposition -100 $787.82 16,100
8 Feb 2026 Jason Pitofsky Senior Vice President Automatic Disposition -1,036 $785.72 4,482
8 Feb 2026 Jason Pitofsky Senior Vice President Derivative Exercise and Sale -1,000 $778.35 4,482

From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.

Short interest, by report

Report dateShares short% of floatDays to cover
15 Oct 2026 2,134,934 2.1% 3.2
30 Sep 2026 2,150,303 2.1% 2.5
15 Sep 2026 2,526,446 2.5% 4.4
31 Aug 2026 2,552,029 2.5% 3.9
14 Aug 2026 2,396,152 2.3% 3.2
31 Jul 2026 3,385,841 3.3% 3.9

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