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Neurogene NGNE

US equityMarket cap rank #3648Biotechnology
$25.31 −$0.34 (-1.33%)
Market closed · Nov 6, 8:20 pm ET · Last extended-hours $25.31 0.00%
Open$26.33
Prev close$25.65
Day range$24.68 – $27.26
Volume324.9K
Market cap$506.49M
P/E (TTM)–
Dividend yield–

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership97.5%-15.72 pts vs. prior quarter
Institutions holding150+7 vs. prior quarter
Insider trades (recent)37 buys / 11 sellsNet buying
Short interest25.45% of floatDays to cover 14.4 · as of 15 Oct 2026
Short-sale volume share25.0%5-day average of daily volume

Short-sale volume as % of daily volume

10%18%26%34%Sep '26Oct '26Nov '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: −$1.03M (4 inflow days, 16 outflow days).

Net flow by order size, last 20 sessions

−$755.8KSuper−$276.5KBig−$350.5KMid−$10.8KSmall

Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.

The five largest holders on file together own 41.3% of shares outstanding.

Largest holders

  • Jennison Associates LLC11.14%
  • Samsara BioCapital LLC8.58%
  • Casdin Capital, LLC7.72%
  • Redmile Group, LLC7.06%
  • RTW Investments, LP6.81%
  • Rachel McMinn6.64%
  • EcoR1 Capital, LLC6.35%
  • BlackRock5.29%

By investor type

  • Hedge Fund38.77%
  • Mutual Fund33.26%
  • VC/PE Fund18.11%
  • Individual/Insider7.01%
  • Public Company4.91%
  • Sovereign Wealth Fund1.84%
  • Private Company0.44%
  • Insurance Company0.12%

Reported short interest has risen from 15.57% to 25.45% of float over the last 6 biweekly reports (31 Jul 2026 to 15 Oct 2026).

Recent institutional activity

HolderTypePeriodShare changeNew stake
Jennison Associates LLC Mutual Fund 2026/Q3 +1,710,500 11.1%
Rachel McMinn Individual/Insider 2026/Q3 +26,656 6.6%
Man Investment Partners (US) LP Mutual Fund 2026/Q3 +24,669 0.1%
Nuveen Asset Management LLC Insurance Company 2026/Q3 +23,857 0.1%
Franklin Resources Mutual Fund 2026/Q3 +204,234 1.0%
Point72 Asset Management, L.P. Hedge Fund 2026/Q3 +141,920 0.7%
Moore Capital Management, LP Hedge Fund 2026/Q3 +141,636 0.7%
Casdin Capital, LLC VC/PE Fund 2026/Q3 +125,000 7.7%
Driehaus Capital Management LLC Mutual Fund 2026/Q3 +110,763 0.7%
Balyasny Asset Management L.P. Hedge Fund 2026/Q3 +100,317 4.1%
Trexquant Investment LP Hedge Fund 2026/Q3 +73,762 0.4%
BlackRock Mutual Fund 2026/Q3 +52,913 5.3%
Dafna Capital Management, LLC Hedge Fund 2026/Q3 +32,397 0.4%
Wellington Management Group Mutual Fund 2026/Q3 +31,393 0.2%
Vanguard Portfolio Management, LLC Mutual Fund 2026/Q3 +30,521 0.5%

Institutional buy/sell activity by reporting period, largest moves first.

Insider transactions

DateInsiderTitleTransactionSharesPriceHeld after
21 Sep 2026 Rachel McMinn Founder, Executive Chair & CEO Derivative Exercise and Retained +756 $25.32 1,329,130
6 Jul 2026 Christine Cvijic Chief Financial Officer Automatic Disposition -4,800 $36.13 37,872
1 Jul 2026 Christine Cvijic Chief Financial Officer Automatic Disposition -4,800 $35.23 42,672
5 May 2026 Christine Cvijic Chief Financial Officer Automatic Disposition -9,600 $32.44 47,472
4 May 2026 Christina Shafer Chief Commercial Officer Other Derivative Acquisition +120,000 $28.94 120,000
25 Mar 2026 Rachel McMinn Founder, Executive Chair & CEO Open Market Disposition -3,352 $22.07 1,302,474
25 Mar 2026 Christine Cvijic Chief Financial Officer Open Market Disposition -2,558 $21.62 57,072
25 Mar 2026 Julie Jordan Chief Medical Officer Open Market Disposition -828 $21.89 3,605
12 Mar 2026 Christine Cvijic Chief Financial Officer Open Market Disposition -4,045 $22.02 52,863
12 Mar 2026 Stuart Cobb Chief Scientific Officer Automatic Disposition -6,797 $22.08 –
26 Feb 2026 Christine Cvijic Chief Financial Officer Automatic Disposition -4,800 $25.11 46,274
19 Feb 2026 Robert Baffi Independent Director Other Derivative Acquisition +12,050 $17.64 12,050
19 Feb 2026 Rohan Palekar Independent Director Other Derivative Acquisition +12,050 $17.64 12,050
19 Feb 2026 Rachel McMinn Founder, Executive Chair & CEO Other Acquisition +25,900 – 49,800
19 Feb 2026 Rachel McMinn Founder, Executive Chair & CEO Other Derivative Acquisition +155,100 $17.64 155,100
19 Feb 2026 Sarah Noonberg Independent Director Other Derivative Acquisition +12,050 $17.64 12,050
19 Feb 2026 Christine Cvijic Chief Financial Officer Other Acquisition +22,000 – 63,569
19 Feb 2026 Christine Cvijic Chief Financial Officer Other Derivative Acquisition +131,900 $17.64 131,900
19 Feb 2026 Cory Freedland Lead Independent Director Other Derivative Acquisition +12,050 $17.64 12,050
19 Feb 2026 Robert Woods Independent Director Other Derivative Acquisition +12,050 $17.64 12,050

From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.

Short interest, by report

Report dateShares short% of floatDays to cover
15 Oct 2026 5,093,623 25.5% 14.4
30 Sep 2026 4,974,749 24.9% 11.7
15 Sep 2026 3,280,172 16.4% 16.9
31 Aug 2026 3,135,369 15.7% 13.6
14 Aug 2026 3,038,441 15.2% 16.8
31 Jul 2026 3,005,232 15.6% 16.2

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