Who holds it, who is betting against it, and where the big money is moving
Net of large-order buying minus selling, in USD. Over this window: −$8.41M (1 inflow days, 19 outflow days).
Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.
The five largest holders on file together own 53.4% of shares outstanding.
Reported short interest has fallen from 3.96% to 2.97% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).
| Holder | Type | Period | Share change | New stake |
|---|---|---|---|---|
| Doliver Advisors, L.P. | Mutual Fund | 2026/Q3 | +30,000 | 0.0% |
| Perceptive Advisors LLC | VC/PE Fund | 2026/Q3 | +815,060 | 8.2% |
| Jefferies Financial Group Inc. | Public Company | 2026/Q3 | +1,447,251 | 4.8% |
| Boxer Capital Management, LLC | Hedge Fund | 2026/Q3 | +475,000 | 0.3% |
| T. Rowe Price Group, Inc. | Mutual Fund | 2026/Q3 | +471,426 | 16.7% |
| Moore Capital Management, LP | Hedge Fund | 2026/Q3 | +192,770 | 0.1% |
| Sectoral Asset Management Inc. | Mutual Fund | 2026/Q3 | +158,098 | 0.2% |
| The Goldman Sachs Group, Inc. | Public Company | 2026/Q3 | +156,962 | 0.3% |
| Qube Research & Technologies Ltd | Mutual Fund | 2026/Q3 | +156,445 | 0.4% |
| Wellington Management Group | Mutual Fund | 2026/Q3 | +85,960 | 1.2% |
| Jane Street Group, LLC | Private Company | 2026/Q3 | +85,605 | 0.1% |
| RTW Investments, LP | Hedge Fund | 2026/Q3 | +76,836 | 9.5% |
| D. E. Shaw & Co., L.P. | Hedge Fund | 2026/Q3 | +59,161 | 0.0% |
| Leap Investments LP | Mutual Fund | 2026/Q3 | +57,713 | 0.1% |
| Macquarie Group Limited | Public Company | 2026/Q3 | +53,500 | 0.0% |
Institutional buy/sell activity by reporting period, largest moves first.
| Date | Insider | Title | Transaction | Shares | Price | Held after |
|---|---|---|---|---|---|---|
| 25 Aug 2026 | Perceptive Advisors LLC | Private Acquisition | +863,060 | $8.69 | 11,246,516 | |
| 13 Aug 2026 | James Pepin | General Counsel | Other Derivative Acquisition | +43,800 | – | 43,800 |
| 13 Aug 2026 | James Pepin | General Counsel | Other Derivative Acquisition | +181,200 | $9.44 | 181,200 |
| 15 Jun 2026 | Michael Atieh | Independent Non-Executive Director | Other Derivative Acquisition | +48,000 | $9.09 | 48,000 |
| 15 Jun 2026 | Peter Chambré | Non-Executive Chairperson | Other Derivative Acquisition | +48,000 | $9.09 | 48,000 |
| 15 Jun 2026 | Heather Mason | Independent Vice Chair of the Board of Directors | Other Derivative Acquisition | +48,000 | $9.09 | 48,000 |
| 15 Jun 2026 | Perceptive Advisors LLC | Other Derivative Acquisition | +48,000 | $9.09 | 48,000 | |
| 15 Jun 2026 | Eliot Forster | Independent Non-Executive Director | Other Derivative Acquisition | +48,000 | $9.09 | 48,000 |
| 15 Jun 2026 | Paul Carter | Independent Non-Executive Director | Other Derivative Acquisition | +48,000 | $9.09 | 48,000 |
| 15 Jun 2026 | Mathias Hothum | Non-Executive Director | Other Derivative Acquisition | +48,000 | $9.09 | 48,000 |
| 15 Jun 2026 | Alise Reicin | Director | Other Derivative Acquisition | +48,000 | $9.09 | 48,000 |
| 15 Jun 2026 | Adam Stone | Independent Non-Executive Director | Other Derivative Acquisition | +48,000 | $9.09 | 48,000 |
| 17 Mar 2026 | Michael Atieh | Independent Non-Executive Director | Initial Statement of Beneficial | +0 | – | 171,500 |
| 17 Mar 2026 | Peter Chambré | Non-Executive Chairperson | Initial Statement of Beneficial | +0 | – | 383,474 |
| 17 Mar 2026 | Heather Mason | Independent Vice Chair of the Board of Directors | Initial Statement of Beneficial | +0 | – | 171,500 |
| 17 Mar 2026 | Perceptive Advisors LLC | Initial Statement of Beneficial | +0 | – | 10,383,456 | |
| 17 Mar 2026 | Harpreet Singh | CEO, MD, Member of Management Board & Executive Director | Initial Statement of Beneficial | +0 | – | 4,509,684 |
| 17 Mar 2026 | Carsten Reinhardt | Chief Development Officer | Initial Statement of Beneficial | +0 | – | 1,065,501 |
| 17 Mar 2026 | Eliot Forster | Independent Non-Executive Director | Initial Statement of Beneficial | +0 | – | 171,500 |
| 17 Mar 2026 | Paul Carter | Independent Non-Executive Director | Initial Statement of Beneficial | +0 | – | 171,500 |
From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.
| Report date | Shares short | % of float | Days to cover |
|---|---|---|---|
| 15 Sep 2026 | 4,438,234 | 3.0% | 8.3 |
| 31 Aug 2026 | 4,853,483 | 3.2% | 6.4 |
| 14 Aug 2026 | 4,921,838 | 3.6% | 14.9 |
| 31 Jul 2026 | 5,028,154 | 3.7% | 11.7 |
| 15 Jul 2026 | 5,047,260 | 3.7% | 13.4 |
| 30 Jun 2026 | 5,408,927 | 4.0% | 13.3 |
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