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4D Molecular Therapeutics FDMT

US equityMarket cap rank #3514Biotechnology
$12.59 +$0.03 (+0.24%)
Pre-market · Oct 8, 8:20 am ET · After hours $12.59 0.00%
Open$12.36
Prev close$12.56
Day range$12.19 – $12.92
Volume603.6K
Market cap$695.52M
P/E (TTM)–
Dividend yield–

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership106.6%-0.76 pts vs. prior quarter
Institutions holding190+2 vs. prior quarter
Insider trades (recent)20 buys / 25 sellsNet selling
Short interest21.74% of floatDays to cover 18.6 · as of 15 Sep 2026
Short-sale volume share19.2%5-day average of daily volume

Short-sale volume as % of daily volume

14%21%27%33%Sep '26Sep '26Oct '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: −$3.90M (7 inflow days, 13 outflow days).

Net flow by order size, last 20 sessions

−$5.2MSuper+$1.3MBig−$505.1KMid−$568.8KSmall

Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.

The five largest holders on file together own 40.6% of shares outstanding.

Largest holders

  • Janus Henderson Group plc10.40%
  • RA Capital Management, L.P.9.14%
  • BlackRock8.23%
  • The Goldman Sachs Group, Inc.6.95%
  • Novo Holdings A/S5.88%
  • State Street Global Advisors5.27%
  • BVF Partners L.P.5.21%
  • T. Rowe Price Group, Inc.4.65%

By investor type

  • Mutual Fund49.76%
  • Hedge Fund27.02%
  • VC/PE Fund17.60%
  • Public Company9.60%
  • Individual/Insider2.84%
  • Private Company1.39%
  • Insurance Company0.89%
  • Government Pension Fund0.25%

Reported short interest has fallen from 25.45% to 21.74% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).

Recent institutional activity

HolderTypePeriodShare changeNew stake
T. Rowe Price Group, Inc. Mutual Fund 2026/Q3 +2,524,309 4.6%
Trails Edge Capital Partners, LP Hedge Fund 2026/Q3 +925,000 4.0%
Adage Capital Management, L.P. Hedge Fund 2026/Q3 +644,047 4.1%
Diadema Partners LP Hedge Fund 2026/Q3 +571,107 1.0%
Janus Henderson Group plc Mutual Fund 2026/Q3 +499,138 10.4%
Catalio Capital Management, LP VC/PE Fund 2026/Q3 +471,254 0.9%
Parkman Healthcare Partners LLC Hedge Fund 2026/Q3 +425,607 1.7%
Citadel Advisors LLC Hedge Fund 2026/Q3 +423,501 1.2%
BlackRock Mutual Fund 2026/Q3 +400,756 8.2%
Schonfeld Strategic Advisors LLC Hedge Fund 2026/Q3 +306,360 0.7%
Acuta Capital Partners, LLC Hedge Fund 2026/Q3 +265,546 0.9%
Bank of America Corporation Public Company 2026/Q3 +265,151 1.2%
Opaleye Management Inc. Hedge Fund 2026/Q3 +222,146 0.6%
Northern Trust Global Investments Mutual Fund 2026/Q3 +220,895 1.0%
Dimensional Fund Advisors Mutual Fund 2026/Q3 +208,034 1.3%

Institutional buy/sell activity by reporting period, largest moves first.

Insider transactions

DateInsiderTitleTransactionSharesPriceHeld after
4 Oct 2026 David Kirn Chief Executive Officer Intent to Sell (Form 144) -58,333 $12.92 –
15 Sep 2026 Scott Bizily Chief Legal & Human Resources Officer and Corporate Secretary Derivative Exercise and Sale -1,635 $13.65 8,617
13 Sep 2026 David Kirn Chief Executive Officer Automatic Disposition -58,333 $13.90 1,367,486
31 Aug 2026 Scott Bizily Chief Legal & Human Resources Officer and Corporate Secretary Derivative Exercise and Sale -584 $14.00 8,617
18 Aug 2026 David Kirn Chief Executive Officer Automatic Disposition -19,076 $16.42 1,425,819
18 Aug 2026 David Kirn Chief Executive Officer Derivative Exercise and Sale -50,000 $16.42 1,425,819
16 Aug 2026 Scott Bizily Chief Legal & Human Resources Officer and Corporate Secretary Derivative Exercise and Sale -3,270 $12.20 8,617
3 Aug 2026 David Kirn Chief Executive Officer Automatic Disposition -26,842 $10.23 1,444,895
2 Aug 2026 David Kirn Chief Executive Officer Automatic Disposition -12,415 $10.05 1,471,737
9 Jul 2026 David Kirn Chief Executive Officer Intent to Sell (Form 144) -15,725 $12.31 –
9 Jul 2026 David Kirn Chief Executive Officer Open Market Disposition -58,333 $12.87 1,484,152
8 Jul 2026 David Kirn Chief Executive Officer Intent to Sell (Form 144) -42,608 $12.89 –
29 Jun 2026 Scott Bizily Chief Legal & Human Resources Officer and Corporate Secretary Derivative Exercise and Sale -6,566 $14.00 8,617
22 Jun 2026 Scott Bizily Chief Legal & Human Resources Officer and Corporate Secretary Derivative Exercise and Sale -9,810 $12.00 8,617
21 Jun 2026 David Kirn Chief Executive Officer Automatic Disposition -114,746 $10.47 1,542,485
16 Jun 2026 Glenn Sblendorio Director Other Derivative Acquisition +50,000 $9.42 50,000
16 Jun 2026 John Milligan Executive Chairperson Other Derivative Acquisition +75,000 $9.42 75,000
16 Jun 2026 Charles Theuer Independent Director Other Derivative Acquisition +50,000 $9.42 50,000
16 Jun 2026 Susannah Gray Independent Director Other Derivative Acquisition +50,000 $9.42 50,000
16 Jun 2026 Jacob Chacko Independent Director Other Derivative Acquisition +50,000 $9.42 50,000

From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.

Short interest, by report

Report dateShares short% of floatDays to cover
15 Sep 2026 12,008,645 21.7% 18.6
31 Aug 2026 12,069,229 21.8% 8.1
14 Aug 2026 12,289,621 22.2% 22.3
31 Jul 2026 12,038,453 23.0% 17.7
15 Jul 2026 11,363,434 21.7% 15.5
30 Jun 2026 13,305,097 25.5% 9.1

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