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CytomX CTMX

US equityMarket cap rank #3673Biotechnology
$2.55 −$0.01 (-0.39%)
Pre-market · Oct 8, 8:20 am ET · After hours $2.54 -0.39%
Open$2.53
Prev close$2.56
Day range$2.52 – $2.65
Volume2.34M
Market cap$555.64M
P/E (TTM)–
Dividend yield–

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership105.2%+0.09 pts vs. prior quarter
Institutions holding201+0 vs. prior quarter
Insider trades (recent)40 buys / 10 sellsNet buying
Short interest17.73% of floatDays to cover 9.3 · as of 15 Sep 2026
Short-sale volume share25.9%5-day average of daily volume

Short-sale volume as % of daily volume

22%25%29%32%Sep '26Sep '26Oct '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: +$3.41M (14 inflow days, 6 outflow days).

Net flow by order size, last 20 sessions

+$921.6KSuper+$2.5MBig+$3.5MMid−$541.8KSmall

Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.

The five largest holders on file together own 47.0% of shares outstanding.

Largest holders

  • FMR15.01%
  • Kynam Capital Management, LP9.96%
  • BlackRock8.06%
  • Longitude Capital Management Co., LLC7.02%
  • Bank of America Corporation6.92%
  • State Street Global Advisors5.39%
  • Perceptive Advisors LLC4.79%
  • Vanguard Capital Management, LLC4.49%

By investor type

  • Mutual Fund49.73%
  • Hedge Fund28.30%
  • VC/PE Fund18.14%
  • Public Company8.31%
  • Individual/Insider0.57%
  • Government Pension Fund0.26%
  • Insurance Company0.18%
  • Private Company0.16%

Reported short interest has risen from 16.34% to 17.73% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).

Recent institutional activity

HolderTypePeriodShare changeNew stake
Nuveen Asset Management LLC Insurance Company 2026/Q3 +374,478 0.2%
BlackRock Mutual Fund 2026/Q3 +12,331,542 8.1%
Kynam Capital Management, LP Hedge Fund 2026/Q3 +6,690,000 10.0%
State Street Global Advisors Mutual Fund 2026/Q3 +6,083,828 5.4%
Bank of America Corporation Public Company 2026/Q3 +4,879,832 6.9%
Geode Capital Management, LLC Mutual Fund 2026/Q3 +2,612,104 2.1%
Wellington Management Group Mutual Fund 2026/Q3 +1,585,976 2.4%
Two Sigma Investments, LP Hedge Fund 2026/Q3 +1,422,487 1.9%
Tudor Investment Corporation Hedge Fund 2026/Q3 +1,380,687 0.6%
Northern Trust Global Investments Mutual Fund 2026/Q3 +1,063,042 0.8%
Vanguard Portfolio Management, LLC Mutual Fund 2026/Q3 +956,412 0.8%
FMR Mutual Fund 2026/Q3 +759,300 15.0%
DV Equities, LLC Mutual Fund 2026/Q3 +714,000 0.3%
Sphera Funds Management Ltd Hedge Fund 2026/Q3 +659,000 0.4%
Goldman Sachs Asset Management, L.P. Mutual Fund 2026/Q3 +603,298 0.3%

Institutional buy/sell activity by reporting period, largest moves first.

Insider transactions

DateInsiderTitleTransactionSharesPriceHeld after
2 Aug 2026 Alejandra Carvajal Chief Legal Officer Other Acquisition +100,000 – 100,000
2 Aug 2026 Alejandra Carvajal Chief Legal Officer Other Derivative Acquisition +450,000 $3.17 450,000
23 Jul 2026 Charles Fuchs Former Independent Director Other Derivative Acquisition +118,000 $3.24 118,000
16 Jun 2026 Elaine Jones Independent Director Other Derivative Acquisition +59,000 $2.96 59,000
16 Jun 2026 Mani Mohindru Independent Director Other Derivative Acquisition +59,000 $2.96 59,000
16 Jun 2026 James Meyers Independent Director Other Derivative Acquisition +59,000 $2.96 59,000
16 Jun 2026 Matthew Young Lead Independent Director Other Derivative Acquisition +59,000 $2.96 59,000
16 Jun 2026 Halley Gilbert Independent Director Other Derivative Acquisition +59,000 $2.96 59,000
16 Jun 2026 Alan Ashworth Independent Director Other Derivative Acquisition +59,000 $2.96 59,000
16 Jun 2026 Zhen Su Director Other Derivative Acquisition +59,000 $2.96 59,000
14 Jun 2026 Christopher Ogden Senior VP of Finance and Accounting, Principal Financial Officer & Principal Accounting Officer Open Market Disposition -1,624 $3.05 128,075
16 Mar 2026 Sean McCarthy Chairperson & CEO Open Market Disposition -118,969 $6.42 714,580
16 Mar 2026 Yu-Waye Chu Chief Medical Officer Open Market Disposition -21,279 $6.42 39,613
16 Mar 2026 Marcia Belvin Senior VP & Chief Scientific Officer Open Market Disposition -31,492 $6.42 164,927
16 Mar 2026 Christopher Ogden Senior VP of Finance and Accounting, Principal Financial Officer & Principal Accounting Officer Open Market Disposition -19,323 $6.42 123,866
1 Feb 2026 Sean McCarthy Chairperson & CEO Other Acquisition +210,000 – 698,750
1 Feb 2026 Sean McCarthy Chairperson & CEO Other Derivative Acquisition +980,000 $6.09 980,000
1 Feb 2026 Rachael Lester Chief Business Officer & Senior VP Other Acquisition +20,000 – 20,000
1 Feb 2026 Rachael Lester Chief Business Officer & Senior VP Other Derivative Acquisition +50,000 $6.09 50,000
1 Feb 2026 Yu-Waye Chu Chief Medical Officer Other Acquisition +75,000 – 206,000

From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.

Short interest, by report

Report dateShares short% of floatDays to cover
15 Sep 2026 38,639,220 17.7% 9.3
31 Aug 2026 33,512,293 15.4% 11.8
14 Aug 2026 34,619,999 15.9% 15.9
31 Jul 2026 35,110,952 16.1% 11.8
15 Jul 2026 40,322,256 18.5% 10.4
30 Jun 2026 35,567,462 16.3% 4.3

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