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Crescent Biopharma CBIO

US equityMarket cap rank #3744Biotechnology
$13.49 −$0.08 (-0.59%)
Market closed · Oct 8, 7:00 am ET · Last extended-hours $13.49 0.00%
Open$13.47
Prev close$13.57
Day range$13.27 – $14.20
Volume1.05M
Market cap$501.07M
P/E (TTM)–
Dividend yield–

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership83.7%-20.75 pts vs. prior quarter
Institutions holding104+3 vs. prior quarter
Insider trades (recent)20 buys / 4 sellsNet buying
Short interest9.17% of floatDays to cover 8.5 · as of 15 Sep 2026
Short-sale volume share25.2%5-day average of daily volume

Short-sale volume as % of daily volume

12%26%40%54%Sep '26Sep '26Oct '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: −$2.60M (13 inflow days, 7 outflow days).

Net flow by order size, last 20 sessions

−$3.4MSuper+$764.8KBig+$606.1KMid+$761.6KSmall

Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.

The five largest holders on file together own 41.2% of shares outstanding.

Largest holders

  • Paragon Therapeutics, Inc.11.68%
  • FMR9.66%
  • Fairmount Funds Management LLC8.41%
  • BVF Partners L.P.6.42%
  • VR Management, LLC4.98%
  • Logos Global Management, L.P.4.44%
  • Forbion Capital Partners B.V.3.92%
  • Balyasny Asset Management L.P.3.89%

By investor type

  • Hedge Fund36.99%
  • Mutual Fund24.63%
  • Private Company11.72%
  • VC/PE Fund9.39%
  • Individual/Insider3.86%
  • Sovereign Wealth Fund0.61%
  • Public Company0.20%
  • Insurance Company0.11%

Reported short interest has fallen from 13.32% to 9.17% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).

Insider transactions

DateInsiderTitleTransactionSharesPriceHeld after
7 Aug 2024 Artal Group S.A. Open Market Disposition -322,361 $0.19 6,317,565
5 Aug 2024 Artal Group S.A. Open Market Disposition -220,255 $0.19 6,639,926
1 Aug 2024 Artal Group S.A. Open Market Disposition -349,764 $0.22 6,860,181
29 Jul 2024 Artal Group S.A. Open Market Disposition -1,379,119 $0.24 7,209,945
24 Jul 2024 Artal Group S.A. Initial Statement of Beneficial +0 – 8,589,064
20 Jun 2024 Edwin Rock Senior VP & Chief Medical Officer Open Market Acquisition +305,000 $0.27 680,403
17 Jun 2024 Brian Hahn Senior Vice President Open Market Acquisition +17,500 $0.25 62,018
30 Apr 2024 Daniel Junius Independent Director Other Derivative Acquisition +40,000 $1.62 40,000
30 Apr 2024 Mark Goldberg Other Derivative Acquisition +40,000 $1.62 40,000
30 Apr 2024 Timothy Pearson Independent Chairperson Other Derivative Acquisition +40,000 $1.62 40,000
30 Apr 2024 Scott Koenig Independent Director Other Derivative Acquisition +40,000 $1.62 40,000
30 Apr 2024 Rachel King Co-Founder Other Derivative Acquisition +40,000 $1.62 40,000
30 Apr 2024 Scott Jackson Independent Director Other Derivative Acquisition +40,000 $1.62 40,000
30 Apr 2024 Patricia Susan Andrews Independent Director Other Derivative Acquisition +40,000 $1.62 40,000
28 Mar 2024 Daniel Junius Independent Director Other Acquisition +5,209 $3.00 98,459
28 Mar 2024 Mark Goldberg Other Acquisition +4,584 $3.00 –
28 Mar 2024 Rachel King Co-Founder Other Acquisition +3,334 $3.00 635,033
11 Jan 2024 Brian Hahn Senior Vice President Other Derivative Acquisition +250,000 $3.11 250,000
11 Jan 2024 Harout Semerjian Chief Executive Officer Other Derivative Acquisition +695,000 $3.11 695,000
11 Jan 2024 Edwin Rock Senior VP & Chief Medical Officer Other Derivative Acquisition +250,000 $3.11 250,000

From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.

Short interest, by report

Report dateShares short% of floatDays to cover
15 Sep 2026 3,407,158 9.2% 8.5
31 Aug 2026 3,172,374 8.5% 19.9
14 Aug 2026 3,216,698 8.7% 17.1
31 Jul 2026 3,465,334 9.3% 8.9
15 Jul 2026 3,743,278 13.6% 9.7
30 Jun 2026 3,673,343 13.3% 7.0

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