Who holds it, who is betting against it, and where the big money is moving
Net of large-order buying minus selling, in USD. Over this window: −$3.22M (3 inflow days, 17 outflow days).
Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.
The five largest holders on file together own 31.6% of shares outstanding.
Reported short interest has risen from 6.87% to 10.64% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).
| Holder | Type | Period | Share change | New stake |
|---|---|---|---|---|
| Nuveen Asset Management LLC | Insurance Company | 2026/Q3 | +56,133 | 0.1% |
| EcoR1 Capital, LLC | Hedge Fund | 2026/Q3 | +2,232,000 | 5.7% |
| BlackRock | Mutual Fund | 2026/Q3 | +1,454,821 | 5.4% |
| Adage Capital Management, L.P. | Hedge Fund | 2026/Q3 | +1,215,000 | 4.1% |
| State Street Global Advisors | Mutual Fund | 2026/Q3 | +486,442 | 1.7% |
| Parkman Healthcare Partners LLC | Hedge Fund | 2026/Q3 | +429,035 | 1.1% |
| Geode Capital Management, LLC | Mutual Fund | 2026/Q3 | +385,300 | 1.7% |
| Affinity Asset Advisors, LLC | Hedge Fund | 2026/Q3 | +350,000 | 2.2% |
| Schonfeld Strategic Advisors LLC | Hedge Fund | 2026/Q3 | +257,631 | 0.7% |
| Vanguard Capital Management, LLC | Mutual Fund | 2026/Q3 | +228,437 | 4.1% |
| Vanguard Portfolio Management, LLC | Mutual Fund | 2026/Q3 | +181,101 | 0.5% |
| Columbia Management Investment Advisers, LLC | Mutual Fund | 2026/Q3 | +177,672 | 0.5% |
| Vivo Capital, LLC | VC/PE Fund | 2026/Q3 | +173,307 | 3.1% |
| Northern Trust Global Investments | Mutual Fund | 2026/Q3 | +159,298 | 1.6% |
| The Goldman Sachs Group, Inc. | Public Company | 2026/Q3 | +98,970 | 0.5% |
Institutional buy/sell activity by reporting period, largest moves first.
| Date | Insider | Title | Transaction | Shares | Price | Held after |
|---|---|---|---|---|---|---|
| 1 Oct 2026 | Nicholas Smith | Chief Financial Officer | Derivative Exercise and Retained | +55,000 | $2.32 | 79,060 |
| 29 Sep 2026 | Nicholas Smith | Chief Financial Officer | Derivative Exercise and Sale | -134,886 | $26.87 | 24,060 |
| 28 Sep 2026 | Nicholas Smith | Chief Financial Officer | Intent to Sell (Form 144) | -134,886 | $26.66 | – |
| 26 May 2026 | Andrew Miller | Director | Other Derivative Acquisition | +26,000 | $20.44 | 26,000 |
| 13 May 2026 | Amit Etkin | Founder, Chairman of the Board, CEO & President | Other Disposition | -400,000 | – | 833,949 |
| 11 May 2026 | Gwill York | Independent Director | Other Derivative Acquisition | +10,958 | $24.63 | 10,958 |
| 11 May 2026 | Andrew Dreyfus | Independent Director | Other Derivative Acquisition | +10,958 | $24.63 | 10,958 |
| 11 May 2026 | Husseini Manji | Non-Employee Independent Director | Other Derivative Acquisition | +10,958 | $24.63 | 10,958 |
| 11 May 2026 | Raymond Sanchez | Director | Other Derivative Acquisition | +10,958 | $24.63 | 10,958 |
| 11 May 2026 | Christopher Cox | Independent Director | Other Derivative Acquisition | +10,958 | $24.63 | 10,958 |
| 28 Feb 2026 | Nicholas Smith | Chief Financial Officer | Sale to Issuer | -2,806 | $19.69 | 24,060 |
| 28 Feb 2026 | Amit Etkin | Founder, Chairman of the Board, CEO & President | Sale to Issuer | -6,227 | $19.69 | 1,233,949 |
| 10 Feb 2026 | Nicholas Smith | Chief Financial Officer | Other Derivative Acquisition | +200,000 | $16.71 | 200,000 |
| 10 Feb 2026 | Amit Etkin | Founder, Chairman of the Board, CEO & President | Other Derivative Acquisition | +306,000 | $16.71 | 306,000 |
| 10 Feb 2026 | Michael Hanley | Chief Operating Officer | Other Derivative Acquisition | +131,000 | $16.71 | 131,000 |
| 10 Feb 2026 | Adam Savitz | Chief Medical Officer | Other Derivative Acquisition | +124,000 | $16.71 | 124,000 |
| 1 Jan 2026 | Gwill York | Independent Director | Other Derivative Acquisition | +5,243 | $16.59 | 5,243 |
| 1 Jan 2026 | Husseini Manji | Non-Employee Independent Director | Other Derivative Acquisition | +4,228 | $16.59 | 4,228 |
| 1 Jan 2026 | Raymond Sanchez | Director | Other Derivative Acquisition | +3,806 | $16.59 | 3,806 |
| 1 Jan 2026 | Christopher Cox | Independent Director | Other Derivative Acquisition | +7,189 | $16.59 | 7,189 |
From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.
| Report date | Shares short | % of float | Days to cover |
|---|---|---|---|
| 15 Sep 2026 | 4,174,082 | 10.6% | 9.1 |
| 31 Aug 2026 | 3,836,359 | 9.8% | 8.1 |
| 14 Aug 2026 | 3,556,066 | 9.1% | 7.5 |
| 31 Jul 2026 | 3,235,210 | 9.2% | 7.5 |
| 15 Jul 2026 | 3,096,805 | 8.8% | 4.3 |
| 30 Jun 2026 | 2,410,038 | 6.9% | 3.0 |
No comments yet — be the first to weigh in on ANRO.