开盘$669.20
昨收$676.94
当日区间$661.60 – $697.78
成交量2.09M
市值$257.42B
市盈率（TTM）36.6
股息率0.26%
股权结构与仓位
谁在持有、谁在做空，以及大资金的流向
机构持股比例92.0%-0.79 个百分点，较上季度
持仓机构数3,234+97 ，较上季度
内部人近期交易22次买入 / 28次卖出净卖出
空头持仓比例1.32% 占流通股回补天数 2.2 · 截至 15 Oct 2026
卖空成交量占比13.4%近5日成交量平均占比
卖空成交量占当日成交量比例
大单净流入，近20个交易日
大单买入减卖出的净额（美元）。该窗口期内：−$118.05M（8个净流入日，12个净流出日）。
按单量净流入，近20个交易日
超大单/大单近似机构级别交易；中单/小单近似散户级别交易。各档买入减卖出净额，按窗口期累计。
已披露的前五大股东合计持有27.0%的流通股。
最大股东
按投资者类型
过去6次双周报告中（31 Jul 2026至15 Oct 2026），空头持仓占流通股比例已基本持稳于1.32%。
近期机构持仓变动
| 股东 | 类型 | 期间 | 持股变动 | 新持股比例 |
|---|---|---|---|---|
| FMR | Mutual Fund | 2026/Q3 | +3,236,781 | 3.3% |
| Dodge & Cox | Mutual Fund | 2026/Q3 | +3,029,037 | 0.8% |
| J.P. Morgan Asset Management, Inc. | Mutual Fund | 2026/Q3 | +1,235,830 | 1.0% |
| SG Americas Securities, LLC | Private Company | 2026/Q3 | +803,535 | 0.3% |
| Brewin Dolphin Wealth Management Limited | Mutual Fund | 2026/Q3 | +637,943 | 0.2% |
| BlackRock | Mutual Fund | 2026/Q3 | +492,440 | 8.4% |
| Putnam LLC | Mutual Fund | 2026/Q3 | +458,159 | 1.2% |
| Glenview Capital Management, LLC | Hedge Fund | 2026/Q3 | +376,715 | 0.2% |
| Arrowstreet Capital, Limited Partnership | Mutual Fund | 2026/Q3 | +373,025 | 0.3% |
| D. E. Shaw & Co., L.P. | Hedge Fund | 2026/Q3 | +338,789 | 0.2% |
| Qube Research & Technologies Ltd | Mutual Fund | 2026/Q3 | +303,806 | 0.1% |
| JPMorgan Chase & Co. | Public Company | 2026/Q3 | +299,775 | 1.3% |
| Blue Sparrow, Llc | Mutual Fund | 2026/Q3 | +271,300 | 0.1% |
| Viking Global Investors LP | Hedge Fund | 2026/Q3 | +269,390 | 0.5% |
| EdgePoint Investment Group Inc. | Hedge Fund | 2026/Q3 | +260,653 | 0.6% |
按报告期列出的机构买卖动态，变动幅度从大到小排列。
内部人交易
| 日期 | 内部人 | 职位 | 交易类型 | 股数 | 价格 | 交易后持股 |
|---|---|---|---|---|---|---|
| 25 Sep 2026 | Scott Sperling | Lead Independent Director | Other Derivative Acquisition | +62 | – | 17,738 |
| 25 Sep 2026 | Jennifer Johnson | Independent Director | Other Derivative Acquisition | +46 | – | 769 |
| 25 Sep 2026 | Karen Lynch | Independent Director | Other Derivative Acquisition | +46 | – | 399 |
| 25 Sep 2026 | Dion Weisler | Independent Director | Other Derivative Acquisition | +55 | – | 2,847 |
| 25 Sep 2026 | R. Keith | Independent Director | Other Derivative Acquisition | +46 | – | 1,378 |
| 30 Aug 2026 | Gianluca Pettiti | President, COO & President of Products and Technologies | Automatic Disposition | -400 | $614.38 | 23,216 |
| 30 Aug 2026 | Gianluca Pettiti | President, COO & President of Products and Technologies | Derivative Exercise and Sale | -3,733 | $614.38 | 23,216 |
| 27 Aug 2026 | Marc Casper | Chairperson & CEO | Sale to Issuer | -1,256 | $622.18 | 126,047 |
| 27 Aug 2026 | Thomas Shropshire | Senior VP and General Counsel | Sale to Issuer | -49 | $622.18 | 6,009 |
| 27 Aug 2026 | Lisa Britt | Chief Human Resources Officer & Senior VP | Sale to Issuer | -393 | $622.18 | 12,939 |
| 27 Aug 2026 | Gianluca Pettiti | President, COO & President of Products and Technologies | Sale to Issuer | -1,034 | $622.18 | 23,216 |
| 27 Aug 2026 | Michael Shafer | Executive VP & President of Biopharma Services | Sale to Issuer | -790 | $622.18 | 17,576 |
| 27 Aug 2026 | Joseph Holmes | Vice President | Sale to Issuer | -49 | $622.18 | 2,470 |
| 27 Aug 2026 | James Meyer | Senior Vice President | Sale to Issuer | -270 | $622.18 | 5,618 |
| 23 Aug 2026 | Marc Casper | Chairperson & CEO | Derivative Exercise and Sale | -275 | $628.74 | 127,303 |
| 21 Aug 2026 | James Meyer | Senior Vice President | Sale to Issuer | -30 | $629.27 | 5,888 |
| 20 Aug 2026 | Marc Casper | Chairperson & CEO | Intent to Sell (Form 144) | -10,000 | $626.91 | – |
| 20 Aug 2026 | Marc Casper | Chairperson & CEO | Derivative Exercise and Sale | -20,000 | $633.99 | 127,303 |
| 19 Aug 2026 | Marc Casper | Chairperson & CEO | Intent to Sell (Form 144) | -10,000 | $629.27 | – |
| 18 Aug 2026 | Lisa Britt | Chief Human Resources Officer & Senior VP | Derivative Exercise and Sale | -11,440 | $613.12 | 13,332 |
数据来自Form 4/Form 144申报文件。负数为减持（出售、赠予或代扣税款股份），正数为增持。
空头持仓（按报告期）
| 报告日期 | 空头股数 | 占流通股比例 | 回补天数 |
|---|---|---|---|
| 15 Oct 2026 | 4,887,534 | 1.3% | 2.2 |
| 30 Sep 2026 | 5,408,135 | 1.5% | 2.1 |
| 15 Sep 2026 | 5,019,933 | 1.4% | 2.7 |
| 31 Aug 2026 | 5,690,588 | 1.5% | 3.4 |
| 14 Aug 2026 | 4,744,180 | 1.3% | 2.9 |
| 31 Jul 2026 | 4,985,877 | 1.3% | 1.9 |
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