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Xenon Pharmaceuticals XENE

US equityMarket cap rank #2343Biotechnology
$37.57 −$0.45 (-1.18%)
Market closed · Oct 6, 12:20 am ET · Last extended-hours $37.72 +0.40%
Open$38.02
Prev close$38.02
Day range$37.00 – $38.23
Volume1.70M
Market cap$3.64B
P/E (TTM)–
Dividend yield–

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership106.4%+0.02 pts vs. prior quarter
Institutions holding379-4 vs. prior quarter
Insider trades (recent)34 buys / 16 sellsNet buying
Short interest6.66% of floatDays to cover 12.2 · as of 15 Sep 2026
Short-sale volume share15.7%5-day average of daily volume

Short-sale volume as % of daily volume

9%13%16%20%Sep '26Sep '26Oct '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: −$16.08M (6 inflow days, 14 outflow days).

The five largest holders on file together own 34.2% of shares outstanding.

Largest holders

  • FMR10.18%
  • BlackRock7.77%
  • Avoro Capital Advisors LLC5.97%
  • T. Rowe Price Group, Inc.5.59%
  • Polar Capital Holdings Plc4.72%
  • Driehaus Capital Management LLC4.56%
  • Janus Henderson Group plc4.32%
  • Capital Research3.33%

By investor type

  • Mutual Fund72.12%
  • Hedge Fund27.18%
  • VC/PE Fund3.52%
  • Public Company1.40%
  • Insurance Company0.84%
  • Government Pension Fund0.73%
  • Private Company0.34%
  • Family Office/Trust0.26%

Reported short interest has risen from 6.47% to 6.66% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).

Short interest, by report

Report dateShares short% of floatDays to cover
15 Sep 2026 6,444,815 6.7% 12.2
31 Aug 2026 6,344,135 6.6% 9.1
14 Aug 2026 5,668,994 5.9% 9.2
31 Jul 2026 5,384,476 5.6% 7.3
15 Jul 2026 6,337,096 6.6% 3.6
30 Jun 2026 6,257,737 6.5% 3.0

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