Who holds it, who is betting against it, and where the big money is moving
Net of large-order buying minus selling, in USD. Over this window: −$332.6K (6 inflow days, 14 outflow days).
Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.
The five largest holders on file together own 70.0% of shares outstanding.
Reported short interest has fallen from 3.92% to 3.68% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).
| Holder | Type | Period | Share change | New stake |
|---|---|---|---|---|
| Nuveen Asset Management LLC | Insurance Company | 2026/Q3 | +14,649 | 0.0% |
| BlackRock | Mutual Fund | 2026/Q3 | +566,973 | 2.1% |
| abrdn plc | Mutual Fund | 2026/Q3 | +272,622 | 1.5% |
| Geode Capital Management, LLC | Mutual Fund | 2026/Q3 | +150,785 | 0.8% |
| State Street Global Advisors | Mutual Fund | 2026/Q3 | +100,311 | 0.4% |
| Vanguard Portfolio Management, LLC | Mutual Fund | 2026/Q3 | +72,132 | 0.2% |
| Northern Trust Global Investments | Mutual Fund | 2026/Q3 | +61,589 | 0.2% |
| J.P. Morgan Asset Management, Inc. | Mutual Fund | 2026/Q3 | +48,967 | 1.8% |
| Millennium Management LLC | Hedge Fund | 2026/Q3 | +38,463 | 1.5% |
| ALPS Advisors, Inc. | Mutual Fund | 2026/Q3 | +33,932 | 0.1% |
| Charles Schwab Investment Management | Mutual Fund | 2026/Q3 | +26,071 | 0.3% |
| BNY Mellon Asset Management | Mutual Fund | 2026/Q3 | +23,944 | 0.1% |
| Virtus Investment Advisers, LLC | Mutual Fund | 2026/Q3 | +17,744 | 0.1% |
| Teachers Insurance and Annuity Association-College Retirement Equities Fund | Mutual Fund | 2026/Q3 | +14,649 | 0.0% |
| Rhumbline Advisers Ltd Partnership | Mutual Fund | 2026/Q3 | +11,844 | 0.0% |
Institutional buy/sell activity by reporting period, largest moves first.
| Date | Insider | Title | Transaction | Shares | Price | Held after |
|---|---|---|---|---|---|---|
| 8 Feb 2026 | New Enterprise Associates, Inc. | Private Acquisition | +937,500 | $16.00 | 7,392,301 | |
| 8 Feb 2026 | New Enterprise Associates, Inc. | Derivative Exercise and Retained | +6,454,801 | – | 7,392,301 | |
| 8 Feb 2026 | RA Capital Management, L.P. | Private Acquisition | +3,690,000 | $16.00 | 8,021,117 | |
| 8 Feb 2026 | RA Capital Management, L.P. | Derivative Exercise and Retained | +4,331,117 | – | 8,021,117 | |
| 8 Feb 2026 | Gilde Healthcare Partners BV | Private Acquisition | +312,500 | $16.00 | 2,187,513 | |
| 8 Feb 2026 | Gilde Healthcare Partners BV | Derivative Exercise and Retained | +1,875,013 | – | 2,187,513 | |
| 8 Feb 2026 | Bilal Khan | Independent Director | Private Acquisition | +135,000 | $16.00 | 276,877 |
| 4 Feb 2026 | Scott Sandell | Initial Statement of Beneficial | +0 | – | 737,962 | |
| 4 Feb 2026 | Geoffrey Pardo | Independent Director | Other Derivative Acquisition | +27,400 | $16.00 | 27,400 |
| 4 Feb 2026 | Mohamad Makhzoumi | Initial Statement of Beneficial | +0 | – | 737,962 | |
| 4 Feb 2026 | Elizabeth O'Farrell | Other Derivative Acquisition | +13,700 | $16.00 | 13,700 | |
| 4 Feb 2026 | Elizabeth O'Farrell | Initial Statement of Beneficial | +0 | – | 65,976 | |
| 4 Feb 2026 | RA Capital Management, L.P. | Other Derivative Acquisition | +27,400 | $16.00 | 27,400 | |
| 4 Feb 2026 | RA Capital Management, L.P. | Initial Statement of Beneficial | +0 | – | 494,647 | |
| 4 Feb 2026 | Jean-Frederic Viret | Chief Financial Officer | Other Derivative Acquisition | +17,500 | $16.00 | 17,500 |
| 4 Feb 2026 | Jean-Frederic Viret | Chief Financial Officer | Initial Statement of Beneficial | +0 | – | 263,907 |
| 4 Feb 2026 | Kirk Nielsen | Other Derivative Acquisition | +27,400 | $16.00 | 27,400 | |
| 4 Feb 2026 | Michael Dybbs | Independent Director | Other Derivative Acquisition | +27,400 | $16.00 | 27,400 |
| 4 Feb 2026 | Malik Kahook | Co-Founder, President, Chief Medical Officer & Executive Chairman | Other Derivative Acquisition | +105,000 | $16.00 | 105,000 |
| 4 Feb 2026 | Malik Kahook | Co-Founder, President, Chief Medical Officer & Executive Chairman | Initial Statement of Beneficial | +0 | – | 434,738 |
From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.
| Report date | Shares short | % of float | Days to cover |
|---|---|---|---|
| 15 Sep 2026 | 1,229,711 | 3.7% | 11.6 |
| 31 Aug 2026 | 1,096,948 | 3.3% | 15.8 |
| 14 Aug 2026 | 1,136,810 | 3.4% | 15.2 |
| 31 Jul 2026 | 1,140,494 | 3.4% | 12.1 |
| 15 Jul 2026 | 1,130,776 | 3.4% | 7.9 |
| 30 Jun 2026 | 1,310,944 | 3.9% | 5.5 |
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