Who holds it, who is betting against it, and where the big money is moving
Net of large-order buying minus selling, in USD. Over this window: −$2.75M (7 inflow days, 13 outflow days).
Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.
The five largest holders on file together own 39.6% of shares outstanding.
Reported short interest has fallen from 17.58% to 17.09% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).
| Holder | Type | Period | Share change | New stake |
|---|---|---|---|---|
| Soleus Capital Management, L.P. | Hedge Fund | 2026/Q3 | +1,833,504 | 9.9% |
| Armistice Capital LLC | Hedge Fund | 2026/Q3 | +392,000 | 9.0% |
| American Century Investment Management | Mutual Fund | 2026/Q3 | +197,287 | 4.0% |
| Macquarie Investment Management Business Trust | Mutual Fund | 2026/Q3 | +195,000 | 1.0% |
| Bridgeway Capital Management, LLC | Mutual Fund | 2026/Q3 | +190,848 | 1.1% |
| BlackRock | Mutual Fund | 2026/Q3 | +170,911 | 10.4% |
| LSV Asset Management | Mutual Fund | 2026/Q3 | +120,159 | 3.9% |
| Centerbook Partners LP | Hedge Fund | 2026/Q3 | +109,575 | 0.6% |
| D. E. Shaw & Co., L.P. | Hedge Fund | 2026/Q3 | +96,861 | 2.9% |
| Morgan Stanley | Public Company | 2026/Q3 | +87,904 | 0.8% |
| Vanguard Portfolio Management, LLC | Mutual Fund | 2026/Q3 | +86,193 | 1.3% |
| UBS Asset Management | Mutual Fund | 2026/Q3 | +72,878 | 0.7% |
| Lionhunter Capital Management, LLC | Family Office/Trust | 2026/Q3 | +63,045 | 0.3% |
| Geode Capital Management, LLC | Mutual Fund | 2026/Q3 | +42,549 | 2.6% |
| Squarepoint OPS LLC | Hedge Fund | 2026/Q3 | +38,550 | 0.4% |
Institutional buy/sell activity by reporting period, largest moves first.
| Date | Insider | Title | Transaction | Shares | Price | Held after |
|---|---|---|---|---|---|---|
| 1 Sep 2026 | Dean Schorno | Chief Financial Officer | Derivative Exercise and Retained | +4,600 | $24.20 | 44,079 |
| 31 Aug 2026 | Raul Rodriguez | Chief Executive Officer | Sale to Issuer | -2,424 | $47.50 | 179,400 |
| 31 Aug 2026 | Dean Schorno | Chief Financial Officer | Sale to Issuer | -928 | $47.50 | 44,079 |
| 31 Aug 2026 | Raymond Furey | General Counsel | Sale to Issuer | -877 | $47.50 | 14,201 |
| 31 Aug 2026 | David Santos | Executive Vice President | Sale to Issuer | -874 | $47.50 | 23,320 |
| 7 Jul 2026 | Alison Hannah | Independent Director | Other Acquisition | +24,400 | – | 24,400 |
| 21 Jun 2026 | Kamil Jackson | Independent Director | Automatic Disposition | -2,500 | $35.00 | 10,125 |
| 16 Jun 2026 | Raul Rodriguez | Chief Executive Officer | Other Derivative Acquisition | +31,700 | $22.49 | 31,700 |
| 16 Jun 2026 | Lisa Rojkjaer | Chief Medical Officer | Other Derivative Acquisition | +16,769 | $22.49 | 7,394 |
| 16 Jun 2026 | Dean Schorno | Chief Financial Officer | Other Derivative Acquisition | +7,394 | $22.49 | 7,394 |
| 16 Jun 2026 | Raymond Furey | General Counsel | Other Derivative Acquisition | +7,394 | $22.49 | 7,394 |
| 16 Jun 2026 | David Santos | Executive Vice President | Other Derivative Acquisition | +7,394 | $22.49 | 7,394 |
| 31 May 2026 | Raul Rodriguez | Chief Executive Officer | Sale to Issuer | -2,424 | $29.86 | 181,138 |
| 31 May 2026 | Lisa Rojkjaer | Chief Medical Officer | Sale to Issuer | -850 | $29.86 | 3,539 |
| 31 May 2026 | Dean Schorno | Chief Financial Officer | Derivative Exercise and Sale | -928 | $29.86 | 38,187 |
| 31 May 2026 | Dean Schorno | Chief Financial Officer | Derivative Exercise and Retained | +2,453 | $18.70 | 38,187 |
| 31 May 2026 | Raymond Furey | General Counsel | Sale to Issuer | -877 | $29.86 | 12,952 |
| 31 May 2026 | David Santos | Executive Vice President | Sale to Issuer | -874 | $29.86 | 22,074 |
| 25 May 2026 | Kamil Jackson | Independent Director | Automatic Disposition | -2,500 | $29.17 | 6,875 |
| 14 May 2026 | Walter Moos | Independent Director | Other Acquisition | +5,750 | – | 5,750 |
From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.
| Report date | Shares short | % of float | Days to cover |
|---|---|---|---|
| 15 Sep 2026 | 3,191,811 | 17.1% | 15.8 |
| 31 Aug 2026 | 3,182,110 | 17.0% | 9.1 |
| 14 Aug 2026 | 3,203,364 | 17.1% | 9.8 |
| 31 Jul 2026 | 3,092,899 | 16.7% | 10.6 |
| 15 Jul 2026 | 3,157,453 | 17.1% | 7.9 |
| 30 Jun 2026 | 3,252,727 | 17.6% | 7.2 |
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