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Mineralys Therapeutics MLYS

US equityMarket cap rank #2754Biotechnology
$23.30 −$0.33 (-1.40%)
Pre-market · Oct 6, 4:10 am ET · After hours $23.40 +0.43%
Open$23.98
Prev close$23.63
Day range$22.97 – $24.00
Volume1.08M
Market cap$2.06B
P/E (TTM)–
Dividend yield–

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership114.4%-0.62 pts vs. prior quarter
Institutions holding284-1 vs. prior quarter
Insider trades (recent)4 buys / 44 sellsNet selling
Short interest10.39% of floatDays to cover 6.4 · as of 15 Sep 2026
Short-sale volume share25.2%5-day average of daily volume

Short-sale volume as % of daily volume

12%19%26%34%Sep '26Sep '26Oct '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: +$1.19M (13 inflow days, 7 outflow days).

The five largest holders on file together own 35.9% of shares outstanding.

Largest holders

  • Catalys Pacific8.82%
  • RA Capital Management, L.P.8.70%
  • BlackRock6.66%
  • Samsara BioCapital LLC6.64%
  • FMR5.10%
  • State Street Global Advisors4.68%
  • Deerfield Management Company, L.P.4.48%
  • Vanguard Capital Management, LLC3.63%

By investor type

  • Mutual Fund48.52%
  • VC/PE Fund31.73%
  • Hedge Fund27.76%
  • Public Company3.99%
  • Private Company1.10%
  • Sovereign Wealth Fund0.93%
  • Individual/Insider0.59%
  • Government Pension Fund0.33%

Reported short interest has fallen from 12.59% to 10.39% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).

Short interest, by report

Report dateShares short% of floatDays to cover
15 Sep 2026 9,181,891 10.4% 6.4
31 Aug 2026 9,332,307 10.6% 11.4
14 Aug 2026 9,645,951 10.9% 13.0
31 Jul 2026 9,313,645 10.6% 15.1
15 Jul 2026 9,552,513 10.8% 9.8
30 Jun 2026 11,098,105 12.6% 5.2

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