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Jade Biosciences JBIO

US equityMarket cap rank #3331Biotechnology
$13.77 +$0.36 (+2.68%)
Pre-market · Oct 8, 9:10 am ET · After hours $13.00 -5.59%
Open$13.19
Prev close$13.41
Day range$13.08 – $14.14
Volume951.3K
Market cap$875.74M
P/E (TTM)–
Dividend yield–

Ownership & positioning

Who holds it, who is betting against it, and where the big money is moving

Institutional ownership115.5%+0.31 pts vs. prior quarter
Institutions holding189+0 vs. prior quarter
Insider trades (recent)23 buys / 6 sellsNet buying
Short interest17.27% of floatDays to cover 11.8 · as of 15 Sep 2026
Short-sale volume share15.9%5-day average of daily volume

Short-sale volume as % of daily volume

12%17%22%27%Sep '26Sep '26Oct '26

Large-order net flow, last 20 sessions

Net of large-order buying minus selling, in USD. Over this window: +$1.58M (8 inflow days, 12 outflow days).

Net flow by order size, last 20 sessions

+$621.1KSuper+$956.4KBig−$175.3KMid+$1.2MSmall

Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.

The five largest holders on file together own 42.2% of shares outstanding.

Largest holders

  • FMR14.35%
  • Janus Henderson Group plc9.86%
  • Fairmount Funds Management LLC7.16%
  • RA Capital Management, L.P.5.77%
  • VR Management, LLC5.06%
  • Paradigm Biocapital Advisors LP4.89%
  • Bellevue Asset Management AG4.81%
  • BlackRock4.40%

By investor type

  • Mutual Fund63.18%
  • Hedge Fund32.51%
  • VC/PE Fund16.75%
  • Public Company2.35%
  • Private Company0.43%
  • Individual/Insider0.28%
  • Government Pension Fund0.17%
  • Insurance Company0.11%

Reported short interest has risen from 13.39% to 17.27% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).

Recent institutional activity

HolderTypePeriodShare changeNew stake
Janus Henderson Group plc Mutual Fund 2026/Q3 +3,167,593 9.9%
Franklin Resources Mutual Fund 2026/Q3 +2,792,045 4.4%
FMR Mutual Fund 2026/Q3 +2,041,454 14.4%
Adage Capital Management, L.P. Hedge Fund 2026/Q3 +1,910,812 3.0%
Polar Capital Holdings Plc Mutual Fund 2026/Q3 +1,846,982 2.9%
State Street Global Advisors Mutual Fund 2026/Q3 +1,679,595 3.7%
J.P. Morgan Asset Management, Inc. Mutual Fund 2026/Q3 +1,432,818 2.3%
Citadel Advisors LLC Hedge Fund 2026/Q3 +792,185 1.5%
Soleus Capital Management, L.P. Hedge Fund 2026/Q3 +753,946 2.4%
Pictet Asset Management Limited Mutual Fund 2026/Q3 +733,768 1.2%
Logos Global Management, L.P. Hedge Fund 2026/Q3 +725,000 1.8%
Foresite Capital Management, LLC VC/PE Fund 2026/Q3 +566,667 1.4%
Vanguard Capital Management, LLC Mutual Fund 2026/Q3 +533,491 4.0%
BlackRock Mutual Fund 2026/Q3 +487,502 4.4%
Balyasny Asset Management L.P. Hedge Fund 2026/Q3 +476,237 1.4%

Institutional buy/sell activity by reporting period, largest moves first.

Insider transactions

DateInsiderTitleTransactionSharesPriceHeld after
24 Jun 2026 Mark Eisner Director Other Derivative Acquisition +47,675 $21.81 47,675
8 Jun 2026 Eric Dobmeier Chairperson Other Derivative Acquisition +34,843 $15.22 34,843
8 Jun 2026 Christopher Cain Director Other Derivative Acquisition +34,843 $15.22 34,843
8 Jun 2026 Erin Lavelle Director Other Derivative Acquisition +34,843 $15.22 34,843
8 Jun 2026 Lawrence Klein Director Other Derivative Acquisition +34,843 $15.22 34,843
8 Jun 2026 Peter Harwin Other Derivative Acquisition +34,843 $15.22 34,843
11 Feb 2026 Tom Frohlich Chief Executive Officer Other Acquisition +78,750 – 78,750
11 Feb 2026 Tom Frohlich Chief Executive Officer Other Derivative Acquisition +472,500 $14.81 472,500
11 Feb 2026 Bradford Dahms Chief Financial Officer Other Acquisition +37,813 – 37,813
11 Feb 2026 Bradford Dahms Chief Financial Officer Other Derivative Acquisition +226,875 $14.81 226,875
11 Feb 2026 Andrew King Chief Scientific Officer & Head of R&D Other Acquisition +41,250 – 41,250
11 Feb 2026 Andrew King Chief Scientific Officer & Head of R&D Other Derivative Acquisition +247,500 $14.81 247,500
11 Feb 2026 Elizabeth Bekiroglu Other Acquisition +28,125 – 28,125
11 Feb 2026 Elizabeth Bekiroglu Other Derivative Acquisition +168,750 $14.81 168,750
5 Oct 2025 Fairmount Funds Management LLC Private Acquisition +1,333,126 $9.14 4,553,494
5 Oct 2025 Fairmount Funds Management LLC Other Derivative Acquisition +855,047 $0.00 855,047
13 Jul 2025 Bradford Dahms Chief Financial Officer Other Derivative Acquisition +526,000 $9.00 526,000
24 Jun 2025 Atlas Venture Advisors, Inc. Intent to Sell (Form 144) -28,977 $10.48 –
24 Jun 2025 Atlas Venture Advisors, Inc. Intent to Sell (Form 144) -235 $10.48 –
23 Jun 2025 Atlas Venture Advisors, Inc. Intent to Sell (Form 144) -16,132 $9.87 –

From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.

Short interest, by report

Report dateShares short% of floatDays to cover
15 Sep 2026 10,982,905 17.3% 11.8
31 Aug 2026 9,994,410 15.7% 16.5
14 Aug 2026 9,650,429 15.2% 10.2
31 Jul 2026 8,690,697 14.3% 11.5
15 Jul 2026 7,528,320 12.4% 7.2
30 Jun 2026 8,148,753 13.4% 4.9

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