Who holds it, who is betting against it, and where the big money is moving
Net of large-order buying minus selling, in USD. Over this window: +$1.58M (8 inflow days, 12 outflow days).
Super/Big orders approximate institutional-size trades; Mid/Small approximate retail-size trades. Net buy minus sell value in each bucket, summed over the window.
The five largest holders on file together own 42.2% of shares outstanding.
Reported short interest has risen from 13.39% to 17.27% of float over the last 6 biweekly reports (30 Jun 2026 to 15 Sep 2026).
| Holder | Type | Period | Share change | New stake |
|---|---|---|---|---|
| Janus Henderson Group plc | Mutual Fund | 2026/Q3 | +3,167,593 | 9.9% |
| Franklin Resources | Mutual Fund | 2026/Q3 | +2,792,045 | 4.4% |
| FMR | Mutual Fund | 2026/Q3 | +2,041,454 | 14.4% |
| Adage Capital Management, L.P. | Hedge Fund | 2026/Q3 | +1,910,812 | 3.0% |
| Polar Capital Holdings Plc | Mutual Fund | 2026/Q3 | +1,846,982 | 2.9% |
| State Street Global Advisors | Mutual Fund | 2026/Q3 | +1,679,595 | 3.7% |
| J.P. Morgan Asset Management, Inc. | Mutual Fund | 2026/Q3 | +1,432,818 | 2.3% |
| Citadel Advisors LLC | Hedge Fund | 2026/Q3 | +792,185 | 1.5% |
| Soleus Capital Management, L.P. | Hedge Fund | 2026/Q3 | +753,946 | 2.4% |
| Pictet Asset Management Limited | Mutual Fund | 2026/Q3 | +733,768 | 1.2% |
| Logos Global Management, L.P. | Hedge Fund | 2026/Q3 | +725,000 | 1.8% |
| Foresite Capital Management, LLC | VC/PE Fund | 2026/Q3 | +566,667 | 1.4% |
| Vanguard Capital Management, LLC | Mutual Fund | 2026/Q3 | +533,491 | 4.0% |
| BlackRock | Mutual Fund | 2026/Q3 | +487,502 | 4.4% |
| Balyasny Asset Management L.P. | Hedge Fund | 2026/Q3 | +476,237 | 1.4% |
Institutional buy/sell activity by reporting period, largest moves first.
| Date | Insider | Title | Transaction | Shares | Price | Held after |
|---|---|---|---|---|---|---|
| 24 Jun 2026 | Mark Eisner | Director | Other Derivative Acquisition | +47,675 | $21.81 | 47,675 |
| 8 Jun 2026 | Eric Dobmeier | Chairperson | Other Derivative Acquisition | +34,843 | $15.22 | 34,843 |
| 8 Jun 2026 | Christopher Cain | Director | Other Derivative Acquisition | +34,843 | $15.22 | 34,843 |
| 8 Jun 2026 | Erin Lavelle | Director | Other Derivative Acquisition | +34,843 | $15.22 | 34,843 |
| 8 Jun 2026 | Lawrence Klein | Director | Other Derivative Acquisition | +34,843 | $15.22 | 34,843 |
| 8 Jun 2026 | Peter Harwin | Other Derivative Acquisition | +34,843 | $15.22 | 34,843 | |
| 11 Feb 2026 | Tom Frohlich | Chief Executive Officer | Other Acquisition | +78,750 | – | 78,750 |
| 11 Feb 2026 | Tom Frohlich | Chief Executive Officer | Other Derivative Acquisition | +472,500 | $14.81 | 472,500 |
| 11 Feb 2026 | Bradford Dahms | Chief Financial Officer | Other Acquisition | +37,813 | – | 37,813 |
| 11 Feb 2026 | Bradford Dahms | Chief Financial Officer | Other Derivative Acquisition | +226,875 | $14.81 | 226,875 |
| 11 Feb 2026 | Andrew King | Chief Scientific Officer & Head of R&D | Other Acquisition | +41,250 | – | 41,250 |
| 11 Feb 2026 | Andrew King | Chief Scientific Officer & Head of R&D | Other Derivative Acquisition | +247,500 | $14.81 | 247,500 |
| 11 Feb 2026 | Elizabeth Bekiroglu | Other Acquisition | +28,125 | – | 28,125 | |
| 11 Feb 2026 | Elizabeth Bekiroglu | Other Derivative Acquisition | +168,750 | $14.81 | 168,750 | |
| 5 Oct 2025 | Fairmount Funds Management LLC | Private Acquisition | +1,333,126 | $9.14 | 4,553,494 | |
| 5 Oct 2025 | Fairmount Funds Management LLC | Other Derivative Acquisition | +855,047 | $0.00 | 855,047 | |
| 13 Jul 2025 | Bradford Dahms | Chief Financial Officer | Other Derivative Acquisition | +526,000 | $9.00 | 526,000 |
| 24 Jun 2025 | Atlas Venture Advisors, Inc. | Intent to Sell (Form 144) | -28,977 | $10.48 | – | |
| 24 Jun 2025 | Atlas Venture Advisors, Inc. | Intent to Sell (Form 144) | -235 | $10.48 | – | |
| 23 Jun 2025 | Atlas Venture Advisors, Inc. | Intent to Sell (Form 144) | -16,132 | $9.87 | – |
From Form 4/Form 144 filings. Negative share counts are disposals (sales, gifts, or shares withheld for taxes); positive are acquisitions.
| Report date | Shares short | % of float | Days to cover |
|---|---|---|---|
| 15 Sep 2026 | 10,982,905 | 17.3% | 11.8 |
| 31 Aug 2026 | 9,994,410 | 15.7% | 16.5 |
| 14 Aug 2026 | 9,650,429 | 15.2% | 10.2 |
| 31 Jul 2026 | 8,690,697 | 14.3% | 11.5 |
| 15 Jul 2026 | 7,528,320 | 12.4% | 7.2 |
| 30 Jun 2026 | 8,148,753 | 13.4% | 4.9 |
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