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Annexon ANNX

US equityMarket cap rank #3449Biotechnology
$4.01 −$0.02 (-0.50%)
Market closed · Oct 8, 7:20 am ET · Last extended-hours $4.05 +1.00%
Open$3.99
Prev close$4.03
Day range$3.91 – $4.18
Volume2.45M
Market cap$760.21M
P/E (TTM)–
Dividend yield–

Fundamentals

Latest reported quarter: Q2, ended Jun 2026

Revenue$0.00
Operating profit-$57.23M-10.6% YoY
Net profit-$55.35M-12.6% YoY
Diluted EPS-$0.28+17.6% YoY
Free cash flow-$48.14M-26.4% YoY
Operating cash flow-$48.01M

Revenue, last 8 quarters

$0.0Sep '24$0.0Dec '24$0.0Mar '25$0.0Jun '25$0.0Sep '25$0.0Dec '25$0.0Mar '26$0.0Jun '26

Net profit, last 8 quarters

$-34.8MSep '24$-48.6MDec '24$-54.4MMar '25$-49.2MJun '25$-54.9MSep '25$-48.3MDec '25$-44.1MMar '26$-55.3MJun '26

Diluted EPS by quarter

-0.25Sep '24-0.33Dec '24-0.37Mar '25-0.34Jun '25-0.37Sep '25-0.28Dec '25-0.23Mar '26-0.28Jun '26

Free cash flow by quarter

$-32.0MSep '24$-36.0MDec '24$-50.1MMar '25$-38.1MJun '25$-52.4MSep '25$-45.9MDec '25$-46.8MMar '26$-48.1MJun '26

Annual revenue

$0.0FY20$0.0FY21$0.0FY22$0.0FY23$0.0FY24$0.0FY25

Profitability & balance sheet

Return on equity-104.3%
Return on assets-78.7%
Return on invested capital-95.4%
Current ratio5.53
Liabilities / assets24.4%
Cash & investments$209.24M
Total debt$21.53M
Net cash (debt)$187.72M

Income statement

Line item 2026 Q2 2026 Q1 2025 ANNUAL 2025 Q4 2025 Q3
Total Operating Revenue $0.00 $0.00 $0.00 $0.00 $0.00
Operating Expense $57.23M $46.05M $216.41M $50.26M $57.02M
Selling and Admin Expenses $10.07M $9.61M $29.06M $4.95M $7.32M
-General & Admin Expense $10.07M $9.61M $29.06M $4.95M $7.32M
Research & Development $46.59M $35.79M $184.70M $42.66M $49.70M
Depreciation & Amortization & Depletion $564,000.00 $657,000.00 $2.65M – –
-Depreciation & Amortization $564,000.00 $657,000.00 $2.65M – –
Operating Profit -$57.23M -$46.05M -$216.41M -$50.26M -$57.02M
Net Non-Operating Interest Income (Expense) $1.88M $1.91M $9.72M $2.00M $2.10M
Non-Operating Interest Income $1.88M $1.91M $9.72M $2.00M $2.10M
Pretax Profit -$55.35M -$44.14M -$206.69M -$48.26M -$54.92M
Net Profit -$55.35M -$44.14M -$206.69M -$48.26M -$54.92M
Profit from Continuing Operations -$55.35M -$44.14M -$206.69M -$48.26M -$54.92M
Net Income to Parent Company -$55.35M -$44.14M -$206.69M -$48.26M -$54.92M
Other Preferred Stock Dividends $0.00 – – – $0.00
Net Income to Common Stockholders -$55.35M -$44.14M -$206.69M -$46.40M -$54.92M
Basic EPS -$0.28 -$0.23 -$1.34 -$0.28 -$0.37
Diluted EPS -$0.28 -$0.23 -$1.34 -$0.28 -$0.37

Balance sheet

Line item 2026 Q2 2026 Q1 2025 ANNUAL 2025 Q4 2025 Q3
Total Assets $246.07M $262.89M $277.57M $277.57M $229.14M
Total Current Assets $212.76M $228.27M $242.19M $242.19M $192.82M
Cash and Cash Equivalents & Short-Term Investments $209.24M $225.03M $238.35M $238.35M $188.72M
-Cash and Cash Equivalents $199.27M $175.21M $162.05M $162.05M $139.42M
-Short Term Investments $9.97M $49.82M $76.29M $76.29M $49.30M
Other Current Assets $3.51M $3.24M $1.24M $1.24M $1.38M
Total Non-Current Assets $33.31M $34.62M $35.38M $35.38M $36.32M
Net PPE $24.01M $24.87M $25.80M $25.80M $26.74M
-Gross PPE $34.43M $34.76M $35.15M $35.15M $35.54M
-Accumulated Depreciation -$10.42M -$9.88M -$9.35M -$9.35M -$8.80M
Other Non-Current Assets $9.30M $9.75M $9.58M $9.58M $9.58M
Total Liabilities $60.01M $58.36M $65.92M $65.92M $67.70M
Total Current Liabilities $38.48M $35.94M $42.63M $42.63M $43.58M
Payables $15.73M $17.53M $14.93M $14.93M $18.22M
-Accounts Payable $15.73M $17.53M $14.93M $14.93M $18.22M
Current Accrued Expenses $15.71M $12.69M $16.77M $16.77M $16.12M
Short-Term Debt and Capital Lease Obligation $3.13M $3.02M $2.91M $2.91M $2.82M
-Current Capital Lease Obligation $3.13M $3.02M $2.91M $2.91M $2.82M
Other Current Liabilities $193,000.00 $452,000.00 $509,000.00 $509,000.00 $260,000.00
Total Non-Current Liabilities $21.53M $22.42M $23.29M $23.29M $24.12M
Long Term Debt and Capital Lease Obligation $21.53M $22.42M $23.29M $23.29M $24.12M
-Long Term Capital Lease Obligation $21.53M $22.42M $23.29M $23.29M $24.12M
Total Equity $186.06M $204.53M $211.65M $211.65M $161.44M
Stockholders' Equity $186.06M $204.53M $211.65M $211.65M $161.44M
Capital Stock $175,000.00 $162,000.00 $149,000.00 $149,000.00 $115,000.00
-Common Stock $175,000.00 $162,000.00 $149,000.00 $149,000.00 $115,000.00
Additional Paid-In Capital $1.20B $1.17B $1.13B $1.13B $1.03B
Retained Earnings -$1.02B -$961.53M -$917.39M -$917.39M -$869.13M
Gains/Losses Not Affecting Retained Earnings -$82,000.00 -$81,000.00 -$29,000.00 -$29,000.00 -$76,000.00
Prepaid Assets – – $2.60M $2.60M $2.72M

Cash flow

Line item 2026 Q2 2026 Q1 2025 ANNUAL 2025 Q4 2025 Q3
Operating Cash Flow -$48.01M -$46.80M -$186.36M -$45.93M -$52.30M
Net cash flow from continuing operations -$48.01M -$46.80M -$186.36M -$45.93M -$52.30M
Net Income from Continuing Operations -$55.35M -$44.14M -$206.69M -$48.26M -$54.92M
Depreciation & Depletion & Amortization $540,000.00 $539,000.00 $2.17M $543,000.00 $546,000.00
Other Non-Cash Items $434,000.00 $418,000.00 $1.52M $402,000.00 $387,000.00
Change in Working Capital $1.81M -$7.14M $4.23M -$1.50M -$1.68M
-Change in Prepaid Assets -$273,000.00 $605,000.00 $598,000.00 $255,000.00 -$498,000.00
-Change in Payables and Accrued Expense $2.87M -$7.25M $11.71M -$1.02M $2.80M
-Change in Other Current Assets $0.00 $275,000.00 -$5.31M $1,000.00 -$3.28M
-Change in Other Current Liabilities -$783,000.00 -$767,000.00 -$2.77M -$737,000.00 -$692,000.00
Net cash flow from investing $39.97M $27.06M $190.05M -$26.52M $45.87M
Net Cash Flow from Continuing Investing Activities $39.97M $27.06M $190.05M -$26.52M $45.87M
Net PPE Purchase and Sale -$137,000.00 $0.00 -$137,000.00 $0.00 -$48,000.00
Net Investment Purchase and Sale $40.10M $27.06M $190.19M -$26.52M $45.92M
Financing Cash Flow $32.10M $32.90M $108.86M $95.08M $13.56M
Net Cash Flow from Continuing Financing Activities $32.10M $32.90M $108.86M $95.08M $13.56M
Net Common Stock Issuance $32.16M $33.60M $109.56M $95.37M $14.19M
Proceeds from Stock Option Exercised $1.05M $229,000.00 $915,000.00 $668,000.00 $3,000.00
Net Other Financing Charges -$1.11M -$936,000.00 -$1.62M -$959,000.00 -$628,000.00
Ending Cash Balance $200.30M $176.24M $163.08M $163.08M $140.45M
Net Change in Cash $24.06M $13.16M $112.55M $22.63M $7.13M
Beginning Cash Balance $176.24M $163.08M $50.53M $140.45M $133.32M
Effect of Exchange Rate Changes $0.00 $1,000.00 $2,000.00 $0.00 $0.00
Free Cash Flow -$48.14M -$46.80M -$186.49M -$45.93M -$52.35M

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