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CSTL vs ICLR

Side-by-side comparison of price performance, valuation, growth, profitability, analyst targets and technical trend.

vsvs
CSTL · Castle Biosciences$32.52 ▼ 4.91%
ICLR · Icon PLC$204.74 ▲ 1.53%

One year, rebased to 100

Each line starts at 100 so growth is directly comparable

467094118142Nov 10, '25May 11, '26Nov 6, '26
  • CSTL -6.4%
  • ICLR +29.8%

Head to head

MetricCSTLICLR
Price$32.52$204.74
Change today▼ 4.91%▲ 1.53%
Market cap$1.00B$15.34B
Return, 3 months+0.5%+23.3%
Return, year to date-16.4%+12.4%
Return, 1 year-1.6%+28.7%
P/E (TTM)-42.835.5
P/B2.11.7
P/E percentile vs own 5y22nd39th
Dividend yield––
Revenue growth (YoY, latest qtr)+20.1%+1.2%
Net profit growth (YoY)-145.5%-64.3%
Gross margin77.3%23.9%
Operating margin-9.0%10.1%
Net margin-5.4%0.5%
Return on equity-4.2%0.4%
Analyst target vs. price+54.4%+15.9%
Analyst buy share100%58%
RSI (14)4366
30-day volatility58.0%59.3%
Max drawdown, 1 year-57.8%-60.5%
Trend readLeaning bearishStrong uptrend
Analyst consensusBuyBuy

Green cells mark the best value in each row where "better" is clear-cut (lower P/E, higher margin). That is a reading of the numbers, not a recommendation. Financials are in each company's reporting currency.

What the numbers say

  • ICLR is the largest of the group by market value.
  • ICLR has returned the most over the past year.
  • CSTL carries the lowest trailing P/E.
  • CSTL is growing revenue fastest.
  • ICLR keeps the most profit per dollar of sales.
  • CSTL has been the calmest stock over the last 30 days.

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